4-Aminoquinoline
Names | |
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IUPAC name
quinolin-4-amine | |
Identifiers | |
578-68-7 | |
ChEMBL | ChEMBL58146 |
ChemSpider | 61751 |
Jmol interactive 3D | Image |
PubChem | 68476 |
UNII | GTE5P5L97N |
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Properties | |
C9H8N2 | |
Molar mass | 144.18 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
verify (what is ?) | |
Infobox references | |
4-Aminoquinoline is a form of aminoquinoline with the amino group at the 4-position of the quinoline.
A variety of derivatives of 4-aminoquinoline are antimalarial agents useful in treating erythrocytic plasmodial infections. Examples include amodiaquine, chloroquine, and hydroxychloroquine.[1]
References
- ↑ Bray PG, Hawley SR, Ward SA (1996). "4-Aminoquinoline resistance of Plasmodium falciparum: insights from the study of amodiaquine uptake". Mol. Pharmacol. 50 (6): 1551–8. PMID 8967977.
External links
- Bourne SA, De Villiers K, Egan TJ (2006). "Three 4-aminoquinolines of antimalarial interest". Acta Crystallogr C 62 (Pt 2): o53–7. doi:10.1107/S0108270105041235. PMID 16456284.
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