4-Aminoquinoline

4-Aminoquinoline
Structural formula of 4-aminoquinoline
Space-filling model of the 4-aminoquinoline molecule
Names
IUPAC name
quinolin-4-amine
Identifiers
578-68-7 N
ChEMBL ChEMBL58146 YesY
ChemSpider 61751 YesY
Jmol interactive 3D Image
PubChem 68476
UNII GTE5P5L97N YesY
Properties
C9H8N2
Molar mass 144.18 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

4-Aminoquinoline is a form of aminoquinoline with the amino group at the 4-position of the quinoline.

A variety of derivatives of 4-aminoquinoline are antimalarial agents useful in treating erythrocytic plasmodial infections. Examples include amodiaquine, chloroquine, and hydroxychloroquine.[1]

References

  1. Bray PG, Hawley SR, Ward SA (1996). "4-Aminoquinoline resistance of Plasmodium falciparum: insights from the study of amodiaquine uptake". Mol. Pharmacol. 50 (6): 1551–8. PMID 8967977.

External links


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