Actinidain
Actinidain (EC 3.4.22.14, actinidin, Actinidia anionic protease, proteinase A2 of Actinidia chinensis) is a type of cysteine protease enzyme found in fruits including kiwifruit (genus Actinidia), pineapple, mango, banana and papaya. This enzyme is part of the papain-like peptidase C1 family.[1][2][3] This enzyme catalyses the following chemical reaction similar to that of papain.
From the kiwi fruit or Chinese gooseberry (Actinidia chinensis).
It is a known allergen and commercially useful as a meat tenderizer.
References
- ↑ Baker, E.N., Boland, M.J., Calder, P.C. and Hardman, M.J. (1980). "The specificity of actinidin and its relationship to the structure of the enzyme". Biochim. Biophys. Acta 616: 30–34. doi:10.1016/0005-2744(80)90260-0. PMID 7002215.
- ↑ Kamphuis, I.G., Drenth, J. and Baker, E.N. (1985). "Thiol proteases. Comparative studies based on the high-resolution structures of papain and actinidin, and on amino acid sequence information for cathepsins B and H, and stem bromelain". J. Mol. Biol. 182: 317–329. doi:10.1016/0022-2836(85)90348-1. PMID 3889350.
- ↑ Baker, E.N. and Drenth, J. (1987). "The thiol proteases: structure and mechanism". In Jurnak, F.A. and McPherson, A. Active Sites of Enzymes. Biological Macromolecules and Assemblies 3. New York: John Wiley and Sons. pp. 314–368. ISBN 0-471-85142-6.
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