Artemotil

Artemotil
Systematic (IUPAC) name
(5aS,6R,8aS,9R,10S,12R,12aR)-10-ethoxy-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene
Clinical data
AHFS/Drugs.com International Drug Names
Pregnancy
category
  • not available
Routes of
administration
Intramuscular injection
Pharmacokinetic data
Metabolism Hepatic
Biological half-life 20 hours
Identifiers
CAS Number 75887-54-6 N
ATC code P01BE04 (WHO)
PubChem CID 3000469
ChemSpider 2272064 N
UNII XGL7GFB9YI YesY
ChEMBL CHEMBL301267 N
Chemical data
Formula C17H28O5
Molar mass 312.401 g/mol
 NYesY (what is this?)  (verify)

Artemotil (INN; also known as β-arteether), is a fast acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria cases. It is a semi-synthetic derivative of artemisinin, a natural product of the Chinese plant Artemisia annua. It is currently only used as a second line drug in severe cases of malaria.

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