Artemotil
Systematic (IUPAC) name | |
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(5aS,6R,8aS,9R,10S,12R,12aR)-10-ethoxy-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene | |
Clinical data | |
AHFS/Drugs.com | International Drug Names |
Pregnancy category |
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Routes of administration | Intramuscular injection |
Pharmacokinetic data | |
Metabolism | Hepatic |
Biological half-life | 20 hours |
Identifiers | |
CAS Number | 75887-54-6 |
ATC code | P01BE04 (WHO) |
PubChem | CID 3000469 |
ChemSpider | 2272064 |
UNII | XGL7GFB9YI |
ChEMBL | CHEMBL301267 |
Chemical data | |
Formula | C17H28O5 |
Molar mass | 312.401 g/mol |
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Artemotil (INN; also known as β-arteether), is a fast acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria cases. It is a semi-synthetic derivative of artemisinin, a natural product of the Chinese plant Artemisia annua. It is currently only used as a second line drug in severe cases of malaria.
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