Beta-farnesene synthase

Beta-farnesene synthase
Identifiers
EC number	4.2.3.47
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Beta-farnesene synthase (EC 4.2.3.47, farnesene synthase, terpene synthase 10, terpene synthase 10-B73, TPS10) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((E)-beta-farnesene-forming).^{[1][2][3][4][5][6][7][8]} This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate $\rightleftharpoons$ (E)-beta-farnesene + diphosphate

References

1. Zhao, B., Lei, L., Vassylyev, D.G., Lin, X., Cane, D.E., Kelly, S.L., Yuan, H., Lamb, D.C. and Waterman, M.R. (2009). "Crystal structure of albaflavenone monooxygenase containing a moonlighting terpene synthase active site". J. Biol. Chem. 284: 36711–36719. doi:10.1074/jbc.M109.064683. PMC 2794785. PMID 19858213.
2. Picaud, S., Brodelius, M. and Brodelius, P.E. (2005). "Expression, purification and characterization of recombinant (E)-β-farnesene synthase from Artemisia annua". Phytochemistry 66 (9): 961–967. doi:10.1016/j.phytochem.2005.03.027. PMID 15896363.
3. Kollner, T.G., Gershenzon, J. and Degenhardt, J. (2009). "Molecular and biochemical evolution of maize terpene synthase 10, an enzyme of indirect defense". Phytochemistry 70 (9): 1139–1145. doi:10.1016/j.phytochem.2009.06.011. PMID 19646721.
4. Schnee, C., Kollner, T.G., Held, M., Turlings, T.C., Gershenzon, J. and Degenhardt, J. (2006). "The products of a single maize sesquiterpene synthase form a volatile defense signal that attracts natural enemies of maize herbivores". Proc. Natl. Acad. Sci. USA 103 (4): 1129–1134. doi:10.1073/pnas.0508027103. PMID 16418295.
5. Maruyama, T., Ito, M. and Honda, G. (2001). "Molecular cloning, functional expression and characterization of (E)-β farnesene synthase from Citrus junos". Biol. Pharm. Bull. 24 (10): 1171–1175. doi:10.1248/bpb.24.1171. PMID 11642326.
6. Crock, J., Wildung, M. and Croteau, R. (1997). "Isolation and bacterial expression of a sesquiterpene synthase cDNA clone from peppermint (Mentha × piperita, L.) that produces the aphid alarm pheromone (E)-β-farnesene". Proc. Natl. Acad. Sci. USA 94 (24): 12833–12838. doi:10.1073/pnas.94.24.12833. PMID 9371761.
7. Schnee, C., Kollner, T.G., Gershenzon, J. and Degenhardt, J. (2002). "The maize gene terpene synthase 1 encodes a sesquiterpene synthase catalyzing the formation of (E)-β-farnesene, (E)-nerolidol, and (E,E)-farnesol after herbivore damage". Plant Physiol. 130 (4): 2049–2060. doi:10.1104/pp.008326. PMID 12481088.
8. Huber, D.P.W., Philippe, R.N., Godard, K.-A., Sturrock, R.N. and Bohlmann, J. (2005). "Characterization of four terpene synthase cDNAs from methyl jasmonate-induced Douglas-fir, Pseudotsuga menziesii". Phytochemistry 66 (12): 1427–1439. doi:10.1016/j.phytochem.2005.04.030. PMID 15921711.

External links

• Beta-farnesene synthase at the US National Library of Medicine Medical Subject Headings (MeSH)