Brutieridin

Brutieridin
Properties
C34H42O19
Molar mass 754.69 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Brutieridin is a flavanone glycoside. Brutieridin was discovered in bergamot orange juice and exhibits statin-like properties[1][2] so the juice seems to have hypolipidemic (lipid-lowering) activity.[1][3][4][5]

References

  1. 1 2 Di Donna, Leonardo; De Luca, Giuseppina; Mazzotti, Fabio; Napoli, Anna; Salerno, Raffaele; Taverna, Domenico; Sindona, Giovanni (2009). "Statin-like Principles of Bergamot Fruit: Isolation of 3-Hydroxymethylglutaryl Flavonoid Glycosides". Journal of Natural Products 72 (7): 1352–1354. doi:10.1021/np900096w. PMID 19572741.
  2. Di Donna, Leonardo; Gallucci, Giselda; Malaj, Naim; Romano, Elvira; Tagarelli, Antonio; Sindona, Giovanni (2011). "Recycling of industrial essential oil waste: Brutieridin and Melitidin, two anticholesterolaemic active principles from bergamot albedo". Food Chemistry 125 (2): 438–441. doi:10.1016/j.foodchem.2010.09.025. ISSN 0308-8146.
  3. Natalizia Miceli, M. R. Mondello, M. T. Monforte, V. Sdrafkakis, P. Dugo, M. L. Crupi, M. F. Taviano, R. De Pasquale and A. Trovato (2007). "Hypolipidemic Effects of Citrus bergamia Risso et Poiteau Juice in Rats Fed a Hypercholesterolemic Diet". J. Agric. Food Chem. 55 (27): 10671–10677. doi:10.1021/jf071772i.
  4. Monica Leopoldini, N. Malaj, M. Toscano, G. Sindona, and N. Russo (2010). "On the Inhibitor Effects of Bergamot Juice Flavonoids Binding to the 3-Hydroxy-3-methylglutaryl-CoA Reductase (HMGR) Enzyme". J. Agric. Food Chem. 58 (19): 10768–10773. doi:10.1021/jf102576j.
  5. Vincenzo Mollace, I. Sacco, E. Janda, C. Malara, D. Ventrice, C. Colica, V. Visalli, S. Muscoli, S. Ragusa, C. Muscoli, D. Rotirotia, F. Romeo (2011). "Hypolipemic and hypoglycaemic activity of bergamot polyphenols: From animal models to human studies". Fitoterapia 82 (3): 309–316. doi:10.1016/j.fitote.2010.10.014. PMID 21056640. PDF

Bibliography

See also


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