Cathepsin V

Cathepsin V
Identifiers
EC number 3.4.22.43
CAS number 223670-00-6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Cathepsin V (EC 3.4.22.43, Cathepsin L2, cathepsin U) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction

The recombinant enzyme hydrolyses proteins (serum albumin, collagen) and synthetic substrates (Z-Phe-Arg-NHMec > Z-Leu-Arg-NHMec > Z-Val-Arg-NHMec)

Cathepsin V is a human lysosomal cysteine endopeptidase.

See also

References

  1. ↑ Brömme, D., Li, Z., Barnes, M. and Mehler, E. (1999). "Human cathepsin V functional expression, tissue distribution, electrostatic surface potential, enzymatic characterization, and chromosomal localization". Biochemistry 38: 2377–2385. doi:10.1021/bi982175f. PMID 10029531.
  2. ↑ Adachi, W., Kawamoto, S., Ohno, I., Nishida, K., Kinoshita, S., Matsubara, K. and Okubo, K. (1998). "Isolation and characterization of human cathepsin V: a major proteinase in corneal epithelium". Invest. Ophthalmol. Vis. Sci. 39 (10): 1789–1796. PMID 9727401.
  3. ↑ Santamaría, I., Velasco, G., Cazorla, M., Fueyo, A., Campo, E. and López-Otín, C. (1998). "Cathepsin L2, a novel human cysteine proteinase produced by breast and colorectal carcinomas". Cancer Res. 58 (8): 1624–1630. PMID 9563472.

External links

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