Ceforanide

Ceforanide

Systematic (IUPAC) name
(6R,7R)-7-{[2-[2-(aminomethyl)phenyl]acetyl]amino}-3- {[1-(carboxymethyl)tetrazol-5-yl]sulfanylmethyl}-8-oxo- 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of administration	Intramuscular
Pharmacokinetic data
Protein binding	80.6%
Metabolism	Nil
Biological half-life	2.6 to 2.98 hours
Excretion	Renal
Identifiers
CAS Number	60925-61-3
ATC code	J01DC11 (WHO)
PubChem	CID 43507
DrugBank	DB00923
ChemSpider	39656
UNII	8M1YF8951V
KEGG	D00259
ChEBI	CHEBI:3495
ChEMBL	CHEMBL1201046
NIAID ChemDB	007642
Chemical data
Formula	C20H21N7O6S2
Molar mass	519.556 g/mol
SMILES O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)Cc3ccccc3CN)CSc4nnnn4CC(=O)O)C(=O)O
InChI InChI=1S/C20H21N7O6S2/c21-6-11-4-2-1-3-10(11)5-13(28)22-15-17(31)27-16(19(32)33)12(8-34-18(15)27)9-35-20-23-24-25-26(20)7-14(29)30/h1-4,15,18H,5-9,21H2,(H,22,28)(H,29,30)(H,32,33)/t15-,18-/m1/s1 Key:SLAYUXIURFNXPG-CRAIPNDOSA-N
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Ceforanide is a second-generation cephalosporin antibiotic.

See also

• Cefotiam

External links

• Crowle A, Sbarbaro J, May M (1988). "Effects of isoniazid and of ceforanide against virulent tubercle bacilli in cultured human macrophages.". Tubercle 69 (1): 15–25. doi:10.1016/0041-3879(88)90036-0. PMID 3140456.
• Campoli-Richards D, Lackner T, Monk J (1987). "Ceforanide. A review of its antibacterial activity, pharmacokinetic properties and clinical efficacy.". Drugs 34 (4): 411–37. doi:10.2165/00003495-198734040-00001. PMID 3315624.
• Cone L, Barton S, Woodard D (1987). "Treatment of scleroma with ceforanide.". Arch Otolaryngol Head Neck Surg 113 (4): 374–6. doi:10.1001/archotol.1987.01860040036012. PMID 3814386.