Flomoxef

Flomoxef

Systematic (IUPAC) name
(6R,7R)-7-[[2-(Difluoromethylsulfanyl)acetyl]amino]-3-[[1-(2-hydroxyethyl)tetrazol-5-yl]sulfanylmethyl]-7-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Number	99665-00-6
ATC code	J01DC14
PubChem	CID 65864
ChemSpider	59274
UNII	V9E5U5XF42
KEGG	D07963
ChEMBL	CHEMBL15413
Chemical data
Formula	C15H18F2N6O7S2
Molar mass	496.46 g/mol
SMILES CO[C@@]1([C@@H]2N(C1=O)C(=C(CO2)CSc3nnnn3CCO)C(=O)O)NC(=O)CSC(F)F
InChI InChI=1S/C15H18F2N6O7S2/c1-29-15(18-8(25)6-31-13(16)17)11(28)23-9(10(26)27)7(4-30-12(15)23)5-32-14-19-20-21-22(14)2-3-24/h12-13,24H,2-6H2,1H3,(H,18,25)(H,26,27)/t12-,15+/m1/s1 Key:UHRBTBZOWWGKMK-DOMZBBRYSA-N
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Flomoxef (INN) is an oxacephem antibiotic.

It has been classified as second-generation^[1] and fourth-generation.^[2]

References

1. Masuda Z, Kurosaki Y, Ishino K, Yamauchi K, Sano S (April 2008). "Pharmacokinetic analysis of flomoxef in children undergoing cardiopulmonary bypass and modified ultrafiltration". Gen Thorac Cardiovasc Surg 56 (4): 163–9. doi:10.1007/s11748-007-0208-5. PMID 18401677.
2. Ito M, Ishigami T (1991). "The meaning of the development of flomoxef and clinical experience in Japan". Infection. 19 Suppl 5: S253–7. doi:10.1007/bf01645536. PMID 1783441.