Chebulic acid

Chebulic acid

Chebulic acid, according to Lee, 2010.[1]
Chebulic acid, according to Klika, 2004.
Chebulic acid, according to Klika, 2004.[2]
Names
IUPAC name
(2R)-2-[(3S)-3-carboxy-5,6,7-trihydroxy-1-oxo-3,4-ihydroisochromen-4-yl]butanedioic acid
Other names
Chebuloyl
Identifiers
23725-05-5 YesY
ChemSpider 27470963 N
Jmol interactive 3D Image
PubChem 25255065
Properties
C14H12O11
Molar mass 356.23 g/mol
Appearance Brown powder
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Chebulic acid is a phenolic compound isolated from the ripe fruits of Terminalia chebula.[3]

This compound possesses an isomer, neochebulic acid.

Chebulic acid is a component of transformed ellagitannins such as chebulagic acid or chebulinic acid.

References

  1. Lee, H. S.; Koo, Y. C.; Suh, H. J.; Kim, K. Y.; Lee, K. W. (2010). "Preventive effects of chebulic acid isolated from Terminalia chebula on advanced glycation endproduct-induced endothelial cell dysfunction". Journal of Ethnopharmacology 131 (3): 567–574. doi:10.1016/j.jep.2010.07.039. PMID 20659546.
  2. The structural and conformational analyses and antioxidant activities of chebulinic acid and its thrice-hydrolyzed derivative, 2,4-chebuloyl-β-D-glucopyranoside, isolated from the fruit of Terminalia chebula. Karel D. Klika, Ammar Saleem, Jari Sinkkonen, Marja Kähkönen, Jyrki Loponen, Petri Tähtinen and Kalevi Pihlaja, ARKIVOC 2004 (vii) 83-105
  3. Lee, H. S.; Jung, S. H.; Yun, B. S.; Lee, K. W. (2006). "Isolation of chebulic acid from Terminalia chebula Retz. And its antioxidant effect in isolated rat hepatocytes". Archives of Toxicology 81 (3): 211–218. doi:10.1007/s00204-006-0139-4. PMID 16932919.
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