Envelysin

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Envelysin (EC 3.4.24.12, sea-urchin-hatching proteinase, hatching enzyme, chorionase, chorion-digesting proteinase, chymostrypsin, sea urchin embryo hatching enzyme) is an enzyme.^[1]^[2]^[3]^[4] This enzyme catalyses the following chemical reaction

Hydrolysis of proteins of the fertilization envelope and dimethylcasein

This enzyme is a glycoprotein from various members of the class Echinoidea.

References

↑ Barrett, D. and Edwards, B.F. (1976). "Hatching enzyme of the sea urchin Strongylocentrotus purpuratus". Methods Enzymol. 45: 354–373. doi:10.1016/s0076-6879(76)45032-2. PMID 1012003.
↑ Lepage, T. and Gache, C. (1989). "Purification and characterization of the sea urchin embryo hatching enzyme". J. Biol. Chem. 264: 4787–4793. PMID 2925668.
↑ Lepage, T. and Gache, C. (1990). "Early expression of a collagenase-like hatching enzyme gene in the sea urchin embryo". EMBO J. 9: 3003–3012. PMID 2167841.
↑ Nomura, K., Tanaka, H., Kikkawa, Y., Yamaguchi, M. and Suzuki, N. (1991). "The specificity of sea urchin hatching enzyme (envelysin) places it in the mammalian matrix metalloproteinase family". Biochemistry 30: 6115–6123. doi:10.1021/bi00239a005. PMID 1711895.

External links

Envelysin at the US National Library of Medicine Medical Subject Headings (MeSH)

Proteases: metalloendopeptidases (EC 3.4.24)

ADAM proteins	Alpha secretases ADAM9 ADAM10 ADAM17 ADAM19 ADAM2 ADAM7 ADAM8 ADAM11 ADAM12 ADAM15 ADAM18 ADAM22 ADAM23 ADAM28 ADAM33 ADAMTS1 ADAMTS2 ADAMTS3 ADAMTS4 ADAMTS5 ADAMTS8 ADAMTS9 ADAMTS10 ADAMTS12 ADAMTS13

Matrix metalloproteinases	Collagenases MMP1 MMP8 Gelatinases MMP2 MMP9 MMP3 MMP7 MMP10 MMP11 MMP12 MMP13 MMP14 MMP15 MMP16 MMP17 MMP19 MMP20 MMP21 MMP23A MMP23B MMP24 MMP25 MMP26 MMP27 MMP28

Other	Neprilysin Procollagen peptidase Thermolysin Pregnancy-associated plasma protein A Bone morphogenetic protein 1 Lysostaphin Insulin-degrading enzyme ZMPSTE24

Proteins: enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases(list) EC2 Transferases(list) EC3 Hydrolases(list) EC4 Lyases(list) EC5 Isomerases(list) EC6 Ligases(list)

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