Colneleate synthase

Colneleate synthase (EC 4.2.1.121, 9-divinyl ether synthase, 9-DES, CYP74D, CYP74D1, CYP74 cytochrome P-450, DES1) is an enzyme with systematic name (8E)-9-((1E,3E)-nona-1,3-dien-1-yloxy)non-8-enoate synthase.^[1]^[2]^[3]^[4] This enzyme catalyses the following chemical reaction

(9S,10E,12Z)-9-hydroperoxyoctadeca-10,12-dienoate

\rightleftharpoons

(8E)-9-[(1E,3Z)-nona-1,3-dien-1-yloxy]non-8-enoate + H₂O

This enzyme is a heme-thiolate protein (P450).

References

↑ Stumpe, M., Kandzia, R., Gobel, C., Rosahl, S. and Feussner, I. (2001). "A pathogen-inducible divinyl ether synthase (CYP74D) from elicitor-treated potato suspension cells". FEBS Lett. 507: 371–376. doi:10.1016/s0014-5793(01)03019-8. PMID 11696374.
↑ Itoh, A. and Howe, G.A. (2001). "Molecular cloning of a divinyl ether synthase. Identification as a CYP74 cytochrome P-450". J. Biol. Chem. 276: 3620–3627. doi:10.1074/jbc.m008964200. PMID 11060314.
↑ Fammartino, A., Cardinale, F., Gobel, C., Mene-Saffrane, L., Fournier, J., Feussner, I. and Esquerre-Tugaye, M.T. (2007). "Characterization of a divinyl ether biosynthetic pathway specifically associated with pathogenesis in tobacco". Plant Physiol. 143: 378–388. doi:10.1104/pp.106.087304. PMID 17085514.
↑ Hamberg, M. (2005). "Hidden stereospecificity in the biosynthesis of divinyl ether fatty acids". FEBS J. 272: 736–743. doi:10.1111/j.1742-4658.2004.04510.x. PMID 15670154.

External links

Colneleate synthase at the US National Library of Medicine Medical Subject Headings (MeSH)

Carbon-oxygen lyases (EC 4.2) (primarily dehydratases)

4.2.1: Hydro-Lyases	Carbonic anhydrase Fumarase Aconitase Enolase Alpha Enolase 2 Enoyl-CoA hydratase/3-Hydroxyacyl ACP dehydrase Methylglutaconyl-CoA hydratase Tryptophan synthase Cystathionine beta synthase Porphobilinogen synthase 3-Isopropylmalate dehydratase Urocanase Uroporphyrinogen III synthase Nitrile hydratase

4.2.2: Acting on polysaccharides	Hyaluronate lyase

4.2.3: Acting on phosphates	Threonine synthase

4.2.99: Other	Carboxymethyloxysuccinate lyase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases(list) EC2 Transferases(list) EC3 Hydrolases(list) EC4 Lyases(list) EC5 Isomerases(list) EC6 Ligases(list)

This article is issued from Wikipedia - version of the Thursday, March 31, 2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.