Diampromide

Diampromide
Systematic (IUPAC) name
N-[2-(methyl-(2-phenylethyl)amino)propyl]-N-phenylpropanamide
Clinical data
Legal status
Identifiers
CAS Number 552-25-0
ATC code none
PubChem CID 62370
DrugBank DB01502 YesY
ChemSpider 56158 YesY
UNII 26G7YC77BU YesY
ChEMBL CHEMBL2106220
Synonyms Diampromide
Chemical data
Formula C21H28N2O
Molar mass 324.46 g/mol
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Diampromide is an opioid analgesic from the ampromide family of drugs, related to other drugs such as propiram. It was invented in the 1960s by American Cyanamid,[1] and can be described as a ring-opened analogue of fentanyl.

Diampromide produces similar effects to other opioids, including analgesia, sedation, dizziness and nausea, and is around the same potency as morphine.[2]

Diampromide is in Schedule I of the Controlled Substances Act 1970 of the United States as a Narcotic with ACSCN 9615 with a zero aggregate manufacturing quota as of 2014. [3] It is listed under the Single Convention for the Control of Narcotic Substances 1961 and is controlled in most countries in the same fashion as is morphine.

References

  1. US Patent 2944081
  2. Ivanovic MD, Micovic IV, Vuckovic S, Prostran M, Todorovic Z, Ivanovic ER, Kiricojevic VD, Djordjevic JB, Dosen-Micovic LJ. The synthesis and pharmacological evaluation of 2,3-seco-fentanyl analogues. Journal of the Serbian Chemical Society. 2004; 69(11): 955-968.
  3. http://www.deadiversion.usdoj.gov/fed_regs/quotas/2014/fr0825.htm



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