Nalorphine dinicotinate

Nalorphine dinicotinate

Systematic (IUPAC) name
(5α,6α)-17-allyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diyl dinicotinate
Clinical data
Legal status	℞ (Prescription only)
Identifiers
CAS Number	3194-25-0
ATC code	None
PubChem	CID 3083791
ChemSpider	2340945
Chemical data
Formula	C31H27N3O5
Molar mass	521.563 g/mol
SMILES O=C(O[C@H]2\C=C/[C@H]6[C@@H]5N(CC[C@@]61c4c(O[C@H]12)c(OC(=O)c3cccnc3)ccc4C5)C\C=C)c7cccnc7
InChI InChI=1S/C31H27N3O5/c1-2-14-34-15-11-31-22-8-10-25(38-30(36)21-6-4-13-33-18-21)28(31)39-27-24(9-7-19(26(27)31)16-23(22)34)37-29(35)20-5-3-12-32-17-20/h2-10,12-13,17-18,22-23,25,28H,1,11,14-16H2/t22-,23+,25-,28-,31-/m0/s1 Key:BFYWWTIGNJJAHF-LTQSXOHQSA-N

Nalorphine dinicotinate (trade name Nimelan), also known as N-allylnormorphine dinicotinate, dinicotinoylnalorphine, or niconalorphine, is a semisynthetic, mixed opioid agonist-antagonist which is described as a narcotic antagonist.^[1][2] It is the 3,6-dinicotinate ester of nalorphine, and is therefore the nalorphine analogue of nicomorphine (which is the 3,6-dinicotinate ester of morphine).

See also

• Diacetylnalorphine

References

1. J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 851–. ISBN 978-1-4757-2085-3.
2. Lemuel B. Wingard (1991). Human pharmacology: molecular-to-clinical. Mosby-Year Book. ISBN 978-0-8016-5632-3. Retrieved 11 May 2012.