This is a list of opioids, opioid antagonists and inverse agonists.
Seedhead of opium poppy with white latex
Crude opiate extracts whole opium products
Polish heroin (Compote, Kompot) •
Diascordium •
B&O Supprettes •
Dover's powder •
Kendal Black Drop •
Laudanum •
Mithridate •
Opium •
Paregoric •
Poppy straw concentrate •
Poppy tea •
Smoking opium •
Theriac
Natural opiates
Opium alkaloids
Codeine •
Morphine •
Oripavine •
Pseudomorphine •
Thebaine
Alkaloid salts mixtures
Pantopon •
Papaveretum (Omnopon) •
Tetrapon
Morphine family
14-Hydroxymorphine [1]•
2,4-Dinitrophenylmorphine •
6-Methyldihydromorphine [2]•
6-Methylenedihydrodesoxymorphine •
6-Acetyldihydromorphine [3]•
Azidomorphine •
Chlornaltrexamine •
Chloroxymorphamine [4]•
Desomorphine (dihydrodesoxymorphine) •
Dihydromorphine •
Ethyldihydromorphine [5]•
Hydromorphinol •
Methyldesorphine •
Morphine methylbromide •
N-Phenethylnordesomorphine •
N-Phenethylnormorphine •
6-Nicotinoyldihydromorphine (metabolite of nicodicodeine) •
RAM-378
| Structures of Morphine family: click to |
|
|
3,6-diesters of morphine
Acetylpropionylmorphine •
3,6-Dibutanoylmorphine •
Diacetyldihydromorphine (dihydroheroin, acetylmorphinol) •
Dibutyrylmorphine •
Dibenzoylmorphine (first designer drug) •
Diformylmorphine •
Dipropanoylmorphine •
Heroin (diacetylmorphine) •
Nicomorphine •
Codeine-dionine family
6-Monoacetylcodeine •
Benzylmorphine •
Codeine methylbromide •
Desocodeine •
Dimethylmorphine (6-O-Methylcodeine) •
Ethyldihydromorphine •
Methyldihydromorphine (dihydroheterocodeine) •
Ethylmorphine (dionine) •
Heterocodeine •
Isocodeine •
Pholcodine (morpholinylethylmorphine) •
Myrophine •
Transisocodeine
Morphinones and morphols
14-Cinnamoyloxycodeinone •
14-Ethoxymetopon •
14-Methoxymetopon •
14-Phenylpropoxymetopon •
3-Acetyloxymorphone •
3,14-Diacetyloxymorphone •
7-Spiroindanyloxymorphone •
8,14-Dihydroxydihydromorphinone •
Acetylcodone •
Acetylmorphone •
α-hydrocodol (=Dihydrocodeine, )•
Benzhydrocodone •
Bromoisopropropyldihydromorphinone cas?•
Codeinone •
Codol (= Codeine Phosphate , )•
Codoxime •
Conorfone (codorphone) •
IBNtxA •
Thebacon (acetyldihydrocodeinone, dihydrocodeinone enol acetate) •
Hydrocodone •
Hydromorphone •
Hydroxycodeine •
Metopon (=Methyldihydromorphinone)•
Morphenol •
Morphinone •
Morphol •
N-Phenethyl-14-ethoxymetopon •
Noroxymorphone •
Oxycodone •
Oxymorphol •
Oxymorphone •
Pentamorphone •
Semorphone
Morphides
α-Chlorocodide (= Chlorocodide) •
β-Chlorocodide •
α-Chloromorphide (= Chloromorphide)•
Bromocodide •
Bromomorphide •
Chlorodihydrocodide •
Chloromorphide •
Codide
| Structures: click to |
| Morphides |
 α-chlorocodide |
 β-chlorocodide |
 Bromomorphide |
 Chlorodihydrocodide. |
 Chloromorphide |
 Codide |
|
|
Dihydrocodeine series
14-Hydroxydihydrocodeine •
Acetyldihydrocodeine •
Dihydrocodeine •
Dihydrodesoxycodeine (desocodeine) •
Dihydroisocodeine •
Nicocodeine •
Nicodicodeine
Nitrogen morphine derivatives
1-Nitrocodeine cas? •
Codeine-N-oxide •
Morphine-N-oxide
Hydrazones
Oxymorphazone
Halogenated morphine derivatives
1-Bromocodeine •
1-Chlorocodeine •
1-Iodomorphine •
| Structures: click to |
| Other open chain opioids |
1-Bromocodeine |
1-Chlorocodeine |
1-Iodomorphine |
|
|
Active opiate metabolites
Codeine-6-glucuronide
Codeine-N-oxide (genocodeine) •
Heroin-7,8-oxide •
Morphine-6-glucuronide •
3-Monoacetylmorphine •
6-Monoacetylmorphine •
Morphine-N-oxide (genomorphine) •
Naltrexol •
Norcodeine •
Normorphine
Morphinan series
3-Hydroxymorphinan
4-Chlorophenylpyridomorphinan •
Cyclorphan •
Levargorphan •
Levorphanol •
Levophenacylmorphan •
Levomethorphan •
Methorphan (racemethorphan) •
Morphanol (racemorphanol) •
Norlevorphanol •
N-Methylmorphinan •
Oxilorphan •
Phenomorphan •
Proxorphan •
Ro4-1539 •
Stephodeline
Xorphanol
Others
1-Nitroaknadinine •
14-episinomenine •
5,6-Dihydronorsalutaridine •
6-Keto Nalbuphine •
Aknadinine •
Butorphanol •
Cephakicine •
Cephasamine •
Cyprodime •
Drotebanol •
Fenfangjine G •
Ketorfanol •
Nalbuphine •
Nalbuphone •
Tannagine
5,9 alpha-diethyl-2-hydroxybenzomorphan (5,9-DEHB) •
8-Carboxamidocyclazocine (8-CAC) •
Alazocine •
Anazocine •
Bremazocine •
Butinazocine •
Carbazocine •
Cogazocine •
Cyclazocine •
Dezocine •
Eptazocine •
Etazocine •
Ethylketazocine •
Fedotozine •
Fluorophen •
Gemazocine •
Ibazocine •
Ketazocine •
Metazocine •
Moxazocine •
Pentazocine •
Phenazocine •
Quadazocine •
SKF-10047
Thiazocine •
Tonazocine •
Volazocine •
Zenazocine
4-Fluoropethidine •
Allylnorpethidine •
Anileridine •
Benzethidine •
Carperidine •
Difenoxin •
Diphenoxylate •
Etoxeridine (carbetidine) •
Furethidine •
Hydroxypethidine (bemidone) •
Morpheridine •
Meperidine-N-oxide •
Oxpheneridine (carbamethidine) •
Pethidine (meperidine) •
Pethidine intermediate A •
Pethidine intermediate B (norpethidine) •
Pethidine intermediate C (pethidinic acid) •
Pheneridine •
Phenoperidine •
Piminodine •
Properidine (ipropethidine) •
Sameridine
Allylprodine •
(α/β)-Meprodine •
Desmethylprodine (MPPP) •
PEPAP •
(α/β)-Prodine •
Prosidol •
Trimeperidine (promedol)
Acetoxyketobemidone •
Droxypropine •
Ketobemidone •
Methylketobemidone •
Propylketobemidone
Others
Alvimopan •
Loperamide •
Picenadol
Amidones
Dextromethadone •
Dipipanone •
Isomethadone •
Levoisomethadone •
Levomethadone •
Methadone •
Methadone intermediate •
Normethadone •
Norpipanone •
Phenadoxone (heptazone) •
Methadols
Acetylmethadol
Alphaacetylmethadol •
Alphamethadol
Betacetylmethadol
Betamethadol
Dimepheptanol (racemethadol) •
Isomethadol
Levacetylmethadol •
Noracymethadol
Moramides
Desmethylmoramide •
Dextromoramide •
Levomoramide •
Moramide intermediate •
Racemoramide
Diethylthiambutene •
Dimethylthiambutene •
Ethylmethylthiambutene •
Piperidylthiambutene •
Pyrrolidinylthiambutene •
Thiambutene •
Phenalkoxams
Dextropropoxyphene (propoxyphene) •
Dimenoxadol •
Dioxaphetyl butyrate •
Levopropoxyphene •
Norpropoxyphene •
Pyrroliphene
Ampromides
Diampromide •
Phenampromide •
Propiram
Others
Embutramide •
IC-26 •
Isoaminile •
Lefetamine •
R-4066
Anilidopiperidines
3-Allylfentanyl •
3-Methylfentanyl •
3-Methylthiofentanyl •
4-Phenylfentanyl •
Alfentanil •
α-Methylacetylfentanyl •
α-Methylfentanyl •
α-Methylthiofentanyl •
Benzylfentanyl •
β-hydroxyfentanyl •
β-hydroxythiofentanyl •
β-Methylfentanyl •
Brifentanil •
Butyrfentanyl •
Carfentanil •
Fentanyl •
Lofentanil •
N-Methylcarfentanil •
Mirfentanil •
Ocfentanil •
Ohmefentanyl •
Parafluorofentanyl •
Phenaridine •
R-30490 •
Remifentanil •
Sufentanil •
Thenylfentanyl •
Thiofentanyl •
Trefentanil
Thienorphine
7-PET •
Acetorphine •
Alletorphine (N-allyl-noretorphine) •
BU-48 •
Buprenorphine •
Buprenorphine-3-glucuronide •
Cyprenorphine •
Dihydroetorphine •
Etorphine •
Homprenorphine •
18,19-Dehydrobuprenorphine (HS-599) •
N-cyclopropylmethylnoretorphine •
Nepenthone •
Norbuprenorphine •
Norbuprenorphine-3-glucuronide •
Thevinone •
Thienorphine
Ethoheptazine •
Meptazinol •
Metheptazine •
Metethoheptazine •
Proheptazine
Pirinitramides
Bezitramide •
Piritramide
Clonitazene •
Etonitazene •
Nitazene
18-Methoxycoronaridine •
7-Acetoxymitragynine •
7-Hydroxymitragynine •
ψ-Akuammigine •
Akuammidine •
Akuammine •
Coronaridine •
Eseroline •
Hodgkinsine •
Ibogaine •
Mitragynine •
Mitragynine pseudoindoxyl •
Noribogaine •
Pericine •
Pseudoakuammigine
3-(dimethylamino)-2,2-dimethyl-1-phenylpropan-1-one •
BW373U86 •
DPI-221 •
DPI-287 •
DPI-3290 •
SNC-80
Big dynorphin •
Dynorphin A •
Dynorphin B •
Leumorphin
Endomorphin-1 •
Endomorphin-2
α-Endorphin •
β-Endorphin •
γ-Endorphin •
α-Neoendorphin •
β-Neoendorphin
DADLE •
DAMGO •
Dermenkephalin •
Met-enkephalin •
Leu-enkephalin
Propeptides
Proenkephalin •
Proendorphin •
Proopiomelanocortin
Others / unknown
Adrenorphin •
Amidorphin •
Biphalin •
Casokefamide •
Casomorphins •
Cytochrophin-4 •
DALDA (Tyr-D-Arg-Phe-Lys-NH2) •
Deltorphin A •
Deltorphin I •
Deltorphin II •
Deprolorphin •
Dermorphin •
DPDPE •
Frakefamide •
Gliadorphin •
Gluten exorphinss •
Hemorphin-4 •
Metkefamide •
Morphiceptin •
Nociceptin •
Octreotide •
Opiorphin •
Rubiscolin •
Soymorphins •
Spinorphin •
TRIMU 5 •
Tynorphin •
Valorphin •
Zyklophin
Others
3-(3-Methoxyphenyl)-3-ethoxycarbonyltropane •
AD-1211 •
AH-7921 •
Axomadol •
Azaprocin •
BDPC •
Bisnortilidine •
BRL-52537 •
Bromadol •
Bromadoline •
Ciprefadol •
Ciramadol •
Doxpicomine •
Enadoline •
Faxeladol •
GR-89696 •
Herkinorin •
ICI-199,441 •
ICI-204,448 •
Ketamine •
KNT-42 •
LPK-26 •
Lufuradom •
Metofoline •
MT-45 •
Desmethylclozapine •
Nexeridine •
NNC 63-0532 •
Nortilidine •
O-Desmethyltramadol •
Phenadone •
Phencyclidine •
Prodilidine •
Profadol •
Ro64-6198 •
Salvinorin A •
Salvinorin B ethoxymethyl ether •
Salvinorin B methoxymethyl ether •
SB-612,111 •
SC-17599 •
RWJ-394,674 •
TAN-67 •
Tapentadol •
Thiobromadol (C-8813) •
Tifluadom •
Tilidine •
Tramadol •
Trimebutine •
U-47,700 •
U-50,488 •
U-69,593 •
Viminol •
1-(4-Nitrophenylethyl)piperidylidene-2-(4-chlorophenyl)sulfonamide (W-18)
4-Caffeoyl-1,5-quinide •
5'-Guanidinonaltrindole •
β-Funaltrexamine •
6β-Naltrexol •
6β-Naltrexol-d4 •
Alvimopan •
AT-076 •
Binaltorphimine •
BU09059 •
Buprenorphine •
Chlornaltrexamine •
Clocinnamox •
Cyclazocine •
Cyprodime •
Diacetylnalorphine •
Diprenorphine (M5050) •
Fedotozine •
ICI-174864 •
J-113,397 •
JDTic •
JTC-801 •
Levallorphan •
LY-2456302 •
LY-255582 •
Methocinnamox •
Methylnaltrexone •
ML350 •
Naldemedine •
Nalfurafine •
Nalmefene •
Nalmexone •
Nalodeine (N-allylnorcodeine) •
Naloxazone •
Naloxegol •
Naloxol •
Naloxonazine •
Naloxone •
Naloxone benzoylhydrazone •
Nalorphine •
Naltrexone •
Naltriben •
Naltrindole •
Norbinaltorphimine •
Oxilorphan •
PF-4455242 •
S-allyl-3-hydroxy-17-thioniamorphinan (SAHTM) •
Samidorphan
SR-16430
6'-Guanidinonaltrindole •
Herkinorin •
TRV130 •
TRV734
Uncategorized opioids
ADL-5859 •
Alimadol •
Amentoflavone •
Anilopam +HCl •
Asimadoline •
Cannabidiol •
Cyproterone acetate •
FE 200665 •
Fedotozine •
HZ-2 •
Kolokol-1 •
Kratom •
Matrine •
MCOPPB •
Menthol •
MT-7716 •
Nalfurafine •
Nalorphine •
Nalorphine dinicotinate •
Proglumide •
Ro65-6570
SoRI-9409
Spiradoline
SR-8993
SR-16435 •
Tetrahydrocannabinol
Combination drug formulations containing opioids
Buprenorphine/naloxone •
Buprenorphine/samidorphan (ALKS-5461) •
Bupropion/naltrexone •
Co-codamol (codeine phosphate/paracetamol) •
Co-codaprin (codeine phosphate/aspirin) •
Co-dydramol (dihydrocodeine tartrate/paracetamol) •
Co-proxamol (dextropropoxyphene/paracetamol) •
Fentanyl/fluanisone •
Hydrocodone/ibuprofen •
Hydrocodone/paracetamol •
Loperamide/simethicone •
Morphine/naltrexone •
Oxycodone/aspirin •
Oxycodone/naloxone
Oxycodone/paracetamol •
See also
External links
- Carbonate derivatives of 14β-hydroxycodeine "viz., 14β-hydroxy-6-O-(methoxycarbonyl)codeine, 6-O-methoxycarbonyl-14β-(methoxycarbonyloxy)codeine, and 14β-acetoxy-6-O-methoxy-carbonylcodeine, potential substrates for ring C modification in morphinane (sic) alkaloids, were synthesized for the first time." Russian Chemical Bulletin. August 2008, Volume 57, Issue 8, pp 1773–1774. Date: 11 Aug 2009; I. V. Evsikova, S. K. Moiseev, P. V. Petrovskii, V. N. Kalinin. Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 8, pp. 1739–1740
References
|
|---|
| Receptor
(ligands) | | MOR |
- PAMs: BMS-986121
- BMS-986122
|
|---|
| | DOR | |
|---|
| | KOR |
- Agonists: 6'-GNTI
- 8-CAC
- 18-MC
- 14-Methoxymetopon
- β-Chlornaltrexamine
- β-Funaltrexamine
- Adrenorphin (metorphamide)
- Akuuamicine
- Alazocine
- Allomatrine
- Asimadoline
- BAM-12P
- BAM-18P
- BAM-22P
- Big dynorphin
- Bremazocine
- BRL-52537
- Butorphan
- Butorphanol
- BW-373U86
- Cebranopadol
- Ciprefadol
- CR665
- Cyclazocine
- Cyclorphan
- Cyprenorphine
- Diamorphine (heroin)
- Diacetylnalorphine
- Difelikefalin
- Dihydroetorphine
- Dihydromorphine
- Diprenorphine
- Dynorphin A
- Dynorphin B (rimorphin)
- Eluxadoline
- Enadoline
- Eptazocine
- Erinacine E
- Ethylketazocine
- Etorphine
- Fedotozine
- Fentanyl
- Gemazocine
- GR-89696
- GR-103545
- Hemorphin-4
- Herkinorin
- HS665
- Hydromorphone
- HZ-2
- Ibogaine
- ICI-199,441
- ICI-204,448
- Ketamine
- Ketazocine
- Laudanosine
- Leumorphin (dynorphin B-29)
- Levallorphan
- Levomethorphan
- Levorphanol
- Lexanopadol
- Lofentanil
- LPK-26
- Lufuradom
- Matrine
- MB-1C-OH
- Menthol
- Metazocine
- Metkefamide
- Mianserin
- Mirtazapine
- Morphine
- Moxazocine
- MR-2034
- N-MPPP
- Nalbuphine
- NalBzOH
- Nalfurafine
- Nalmefene
- Nalodeine (N-allylnorcodeine)
- Nalorphine
- Naltriben
- Niravoline
- Norbuprenorphine
- Norbuprenorphine-3-glucuronide
- Noribogaine
- Norketamine
- O-Desmethyltramadol
- Oripavine
- Oxilorphan
- Oxycodone
- Pentazocine
- Pethidine (meperidine)
- Phenazocine
- Proxorphan
- Racemethorphan
- Racemorphan
- RB-64
- Salvinorin A (salvia)
- Salvinorin B ethoxymethyl ether
- Salvinorin B methoxymethyl ether
- Samidorphan
- SKF-10047
- Spiradoline (U-62,066)
- TH-030418
- Thienorphine
- Tifluadom
- Tricyclic antidepressants (e.g., amitriptyline, desipramine, imipramine, nortriptyline)
- U-50,488
- U-54,494A
- U-69,593
- Xorphanol
|
|---|
| | NOP | |
|---|
| Unsorted /
unknown | |
|---|
|
|---|
| Enzyme
(inhibitors) | |
|---|
| | Others |
- Others: Kyotorphin (met-enkephalin releaser/degradation stabilizer)
|
|---|
| See also: Neuropeptidergics • Peptidergics |
|
.svg.png)
-2%2C2-dimethyl-1-phenylpropan-1-one.jpg)
