Dimethylthiambutene
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| Systematic (IUPAC) name | |
|---|---|
|
(RS)-N,N-dimethyl-4,4-dithiophen-2-yl-but-3-en-2-amine | |
| Clinical data | |
| Legal status | |
| Legal status |
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| Identifiers | |
| CAS Number |
524-84-5  |
| ATC code | none |
| PubChem | CID 10668 |
| DrugBank |
DB01444 |
| ChemSpider |
10218 |
| UNII |
915D88LM9O |
| ChEBI |
CHEBI:59781 |
| ChEMBL | CHEMBL2106265 |
| Chemical data | |
| Formula | C14H17NS2 |
| Molar mass | 263.424 g/mol |
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| Physical data | |
| Melting point | 169 to 170 °C (336 to 338 °F) |
| (verify) | |
Dimethylthiambutene (N,N-Dimethyl-1-methyl-3,3-di-2-thienylallylamine, DMTB, trade names Ohton, Aminobutene, Dimethibutin, Kobaton, Takaton, Dimethibutin) is an opioid analgesic drug, most often used in veterinary medicine in Japan and to a lesser extent in other countries in the region and around the world. It is the most prominent and widely used of the thiambutenes, a series of open-chain opioids structurally related to methadone which are also called the thienyl derivative opioids which also includes diethylthiambutene and ethylmethylthiambutene, as well as the non-opioid cough suppressant tipepidine.
Dimethylthiambutene was developed in the United Kingdom in the late 1940s[1] and introduced to the market by Burroughs-Wellcome in 1951. Dimethylthiambutene is now under international control under the UN Single Convention on Narcotic Drugs 1961, the laws governing habit-forming substances in virtually all countries and Schedule I of the US Controlled Substances Act of 1970 due to high abuse potential and never being introduced clinically in the United States; other countries regulate it much as morphine or diamorphine. Its DEA ACSCN is 9619 and it had a zero manufacturing quota in 2013.
See also
References
- ↑ U.S. Patent 2,561,899 - Dithienyl Allyl Amines
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