List of Schedule I drugs (US)

This is the list of Schedule I drugs as defined by the United States Controlled Substances Act.^[1] The following findings are required for drugs to be placed in this schedule:^[2]

1. The drug or other substance has a high potential for abuse.
2. The drug or other substance has no currently accepted medical use in treatment in the United States.
3. There is a lack of accepted safety for use of the drug or other substance under medical supervision.

Except as specifically authorized, it is illegal for any person:

1. to manufacture, distribute, or dispense, or possess with intent to manufacture, distribute, or dispense, a controlled substance; or
2. to create, distribute, or dispense, or possess with intent to distribute or dispense, a counterfeit substance.^[3]

The complete list of Schedule I drugs follows.^[1] The Administrative Controlled Substances Code Number for each drug is included.

Opioids

ACSCN	Drug
9815	Acetyl-alpha-methylfentanyl (N-[1-(1-methyl-2-phenethyl)-4-piperidinyl]-N-phenylacetamide)
9601	Acetylmethadol
9602	Allylprodine
9603	Alphacetylmethadol (except levo-alphacetylmethadol also known as levo-alpha-acetylmethadol, levomethadyl acetate, or LAAM)
9604	Alphameprodine
9605	Alphamethadol
9814	Alpha-methylfentanyl (N-[1-(alpha-methyl-beta-phenyl)ethyl-4-piperidyl] propionanilide; 1-(1-methyl-2-phenylethyl)-4-(N-propanilido) piperidine)
9832	Alpha-methylthiofentanyl (N-[1-methyl-2-(2-thienyl)ethyl-4- piperidinyl]-N-phenylpropanamide)
9606	Benzethidine
9607	Betacetylmethadol
9830	Beta-hydroxyfentanyl (N-[1-(2-hydroxy-2-phenethyl)-4- piperidinyl]-N-phenylpropanamide)
9831	Beta-hydroxy-3-methylfentanyl (other name: N-[1-(2-hydroxy-2- phenethyl)-3-methyl-4-piperidinyl]-N-phenylpropanamide
9608	Betameprodine
9609	Betamethadol
9611	Betaprodine
9612	Clonitazene
9613	Dextromoramide
9615	Diampromide
9616	Diethylthiambutene
9168	Difenoxin
9617	Dimenoxadol
9618	Dimepheptanol
9619	Dimethylthiambutene
9621	Dioxaphetyl butyrate
9622	Dipipanone
9623	Ethylmethylthiambutene
9624	Etonitazene
9625	Etoxeridine
9626	Furethidine
9627	Hydroxypethidine
9628	Ketobemidone
9629	Levomoramide
9631	Levophenacylmorphan
9813	3-Methylfentanyl (N-[3-methyl-1-(2-phenylethyl)-4-piperidyl]-N-phenylpropanamide)
9833	3-methylthiofentanyl (N-[(3-methyl-1-(2-thienyl)ethyl-4-piperidinyl]-N-phenylpropanamide)
9632	Morpheridine
9661	MPPP (1-methyl-4-phenyl-4-propionoxypiperidine)
9633	Noracymethadol
9634	Norlevorphanol
9635	Normethadone
9636	Norpipanone
9812	Para-fluorofentanyl (N-(4-fluorophenyl)-N-[1-(2-phenethyl)-4-piperidinyl] propanamide
9663	PEPAP (1-(-2-phenethyl)-4-phenyl-4-acetoxypiperidine
9637	Phenadoxone
9638	Phenampromide
9647	Phenomorphan
9641	Phenoperidine
9642	Piritramide
9643	Proheptazine
9644	Properidine
9649	Propiram
9645	Racemoramide
9835	Thiofentanyl (N-phenyl-N-[1-(2-thienyl)ethyl-4-piperidinyl]-propanamide
9750	Tilidine
9646	Trimeperidine

Opium derivatives

Heroin powder

ACSCN	Drug
9319	Acetorphine
9051	Acetyldihydrocodeine
9052	Benzylmorphine
9070	Codeine methylbromide
9053	Codeine-N-Oxide
9054	Cyprenorphine
9055	Desomorphine
9145	Dihydromorphine
9335	Drotebanol
9056	Etorphine (except hydrochloride salt)
9200	Heroin (diacetylmorphine)
9301	Hydromorphinol
9302	Methyldesorphine
9304	Methyldihydromorphine
9305	Morphine methylbromide
9306	Morphine methylsulfonate
9307	Morphine-N-Oxide
9308	Myrophine
9309	Nicocodeine
9312	Nicomorphine
9313	Normorphine
9314	Pholcodine
9315	Thebacon

Hallucinogenic or psychedelic substances

Peyote

Psilocybe zapotecorum, one of many species of psilocybin mushrooms

cannabis contains the psychoactive substance, tetrahydrocannabinol (THC).

ACSCN	Drug
7249	Alpha-Ethyltryptamine (αET)
7391	4-bromo-2,5-dimethoxy-amphetamine (DOB)
7392	4-Bromo-2,5-dimethoxyphenethylamine (2C-B)
7396	2,5-dimethoxyamphetamine (DOA)
7399	2,5-Dimethoxy-4-ethylamphetamine (DOE)
7348	2,5-dimethoxy-4-(n)-propylthiophenethylamine (2C-T-7), its optical isomers, salts and salts of isomers
7411	4-methoxyamphetamine (PMA)
7401	5-methoxy-3,4-methylenedioxyamphetamine (MMDA)
7395	4-methyl-2,5-dimethoxyamphetamine (DOM; STP)
7400	3,4-methylenedioxyamphetamine (MDA)
7405	3,4-methylenedioxymethamphetamine (MDMA)
7404	3,4-methylenedioxy-N-ethylamphetamine (MDEA; MDE)
7402	N-hydroxy-3,4-methylenedioxyamphetamine (N-hydroxy MDA)
7390	3,4,5-trimethoxyamphetamine (TMA)
7431	5-methoxy-N,N-dimethyltryptamine (5-methoxy-3-[2-(dimethylamino)ethyl]indole; 5-MeO-DMT)
7432	Alpha-methyltryptamine (αMT)
7433	Bufotenine
7434	Diethyltryptamine (DET)
7435	Dimethyltryptamine(DMT)
7439	5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT), its isomers, salts and salts of isomers
7260	Ibogaine
7315	Lysergic acid diethylamide (LSD)
7360	Cannabis
7381	Mescaline
7374	Parahexyl
7415	Peyote
7482	N-ethyl-3-piperidyl benzilate
7484	N-methyl-3-piperidyl benzilate
7437	Psilocybin
7438	Psilocin
7370	Tetrahydrocannabinol (THC)
7455	Ethylamine analog of phencyclidine (Eticyclidine; PCE)
7458	Pyrrolidine analog of phencyclidine (PCPy)
7470	Thiophene analog of phencyclidine (TCP)
7473	1-[1-(2-thienyl)cyclohexyl]pyrrolidine (TCPy)
1248	4-methylmethcathinone (Mephedrone)
7535	3,4-methylenedioxypyrovalerone (MDPV)
7509	2-(2,5-Dimethoxy-4-ethylphenyl)ethanamine (2C-E)
7508	2-(2,5-Dimethoxy-4-methylphenyl)ethanamine (2C-D)
7519	2-(4-Chloro-2,5-dimethoxyphenyl)ethanamine (2C-C)
7518	2-(4-Iodo-2,5-dimethoxyphenyl)ethanamine (2C-I)
7385	2-[4-(Ethylthio)-2,5-dimethoxyphenyl]ethanamine (2C-T-2)
7532	2-[4-(Isopropylthio)-2,5-dimethoxyphenyl]ethanamine (2C-T-4)
7517	2-(2,5-Dimethoxyphenyl)ethanamine (2C-H)
7521	2-(2,5-Dimethoxy-4-nitro-phenyl)ethanamine (2C-N)
7524	2-(2,5-Dimethoxy-4-(n)-propylphenyl)ethanamine (2C-P)
7540	3,4-Methylenedioxy-N-methylcathinone (Methylone)

Depressants

gamma-Hydroxybutyrate powder

ACSCN	Drug
2010	gamma-Hydroxybutyric acid (GHB; sodium oxybate; sodium oxybutyrate)
2572	Mecloqualone
2565	Methaqualone

Stimulants

Aminorex

Products containing BZP.

ACSCN	Drug
1585	Aminorex (aminoxaphen; 2-amino-5-phenyl-2- oxazoline; or 4,5-dihydro-5-phenly-2-oxazolamine)
7493	N-benzylpiperazine (some other names: BZP; 1-benzylpiperazine), its optical isomers, salts and salts of isomers
1235	Cathinone
1503	Fenethylline
1237	Methcathinone (Some other names: 2-(methylamino)-propiophenone; alpha-(methylamino)propiophenone; 2-(methylamino)-1-phenylpropan-1-one; alpha-N-methylaminopropiophenone; monomethylpropion; ephedrone; N-methylcathinone; methylcathinone; AL-464; AL-422; AL-463 and UR1432), its salts, optical isomers and salts of optical isomers
1590	(+/-)cis-4-methylaminorex
1475	N-ethylamphetamine
1480	N,N-dimethylamphetamine (also known as N,N-alpha-trimethyl-benzeneethanamine; N,N-alpha-trimethylphenethylamine)

Cannabimimetic agents

ACSCN	Drug
7297	5-(1,1-dimethylheptyl)-2-[(1R,3S)-3-hydroxycyclohexyl]-phenol (CP-47,497)
7298	5-(1,1-dimethyloctyl)-2-[(1R,3S)-3-hydroxycyclohexyl]-phenol (cannabicyclohexanol or CP-47,497 C8-homolog)
7118	1-pentyl-3-(1-naphthoyl)indole (JWH-018 and AM678)
7173	1-butyl-3-(1-naphthoyl)indole (JWH-073)
7019	1-hexyl-3-(1-naphthoyl)indole (JWH-019)
7200	1-[2-(4-morpholinyl)ethyl]-3-(1-naphthoyl)indole (JWH-200)
6250	1-pentyl-3-(2-methoxyphenylacetyl)indole (JWH-250)
7081	1-pentyl-3-[1-(4-methoxynaphthoyl)]indole (JWH-081)
7122	1-pentyl-3-(4-methyl-1-naphthoyl)indole (JWH-122)
7398	1-pentyl-3-(4-chloro-1-naphthoyl)indole (JWH-398)
7201	1-(5-fluoropentyl)-3-(1-naphthoyl)indole (AM2201)
7694	1-(5-fluoropentyl)-3-(2-iodobenzoyl)indole (AM694)
7104	1-pentyl-3-[(4-methoxy)-benzoyl]indole (SR-19 and RCS-4)
7008	1-cyclohexylethyl-3-(2-methoxyphenylacetyl)indole 7008 (SR-18 and RCS-8)
7203	1-pentyl-3-(2-chlorophenylacetyl)indole (JWH-203)

Temporary/emergency listings

These items are listed by the Secretary of Health and Human Services pursuant to 21 CFR 1308.49.^[4][5]

ACSCN	Drug
7144	(1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone, its optical, positional, and geometric isomers, salts and salts of isomers (UR-144, 1-pentyl-3-(2,2,3,3-tetramethylcyclopropoyl)indole)
7011	[1-(5-fluoro-pentyl)-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)methanone, its optical, positional, and geometric isomers, salts and salts of isomers (5-fluoro-UR-144, 5-F-UR-144, XLR-11, 1-(5-fluoro-pentyl)-3-(2,2,3,3-tetramethylcyclopropoyl)indole)
7048	N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide, its optical, positional, and geometric isomers, salts and salts of isomers (APINACA, AKB-48)
7222	Quinolin-8-yl 1-pentyl-1H-indole-3-carboxylate (QUPIC, PB-22)[6]
7225	Quinolin-8-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate (5-fluoro-PB-22; 5F-PB-22)[6]
7012	N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide (AB-FUBINACA)[6]
7035	N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3-carboxamide (ADB-PINACA)[6]
7031	N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-1H-indazole-3-carboxamide (AB-CHMINACA)[7]
7023	N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3-carboxamide (AB-PINACA)[7]
7024	[1-(5-fluoropentyl)-1H-indazol-3-yl](naphthalen-1-yl)methanone (THJ-2201)[7]
7538	2-(4-iodo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine (25I-NBOMe; 2C-I-NBOMe; 25I; Cimbi-5)[8]
7537	2-(4-chloro-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine (25C-NBOMe; 2C-C-NBOMe; 25C; Cimbi-82)[8]
7536	2-(4-bromo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine (25B-NBOMe; 2C-B-NBOMe; 25B; Cimbi-36)[8]
9821	Acetylfentanyl (N-(1-phenethylpiperidin-4-yl)-N-phenylacetamide)[9]

References

1. 21 CFR 1308.11 (CSA Sched I) with changes through 77 FR 64032 (Oct 18, 2012). Retrieved September 6, 2013.
2. 21 U.S.C. § 812(b)(1) United States Code via Cornell University's Legal Information Institute. Retrieved on 2007-10-02.
3. Drug Enforcement Administration (DEA) (22 Jan 2002). "Title 21 — Food and Drugs Chapter 13 - Drug Abuse Prevention and Control Subchapter I — Control and Enforcement Part D — Offenses and Penalties: Sec. 841. Prohibited Acts A(a)". Retrieved 23 Oct 2009.
4. Code of Federal Regulations, 2012-04-01
5. The first 8 items in the temporary section of the schedule shown on the DEA website are not included here because they are duplicates of entries in the tables above. Presumably, this is because they were made permanent and copied there at some point, but inadvertently not deleted from this temporary listing section.
6. "Schedules of controlled substances: temporary placement of four synthetic cannabinoids into Schedule I. Final order". Fed Regist. 79 (27): 7577–7582. Feb 10, 2014. PMID 24605391.
7. Drug Enforcement Administration, Department of Justice (2015). "Schedules of controlled substances: Temporary placement of three synthetic cannabinoids into schedule I. Final order". Federal register 80 (20): 5042–7. PMID 25730924.
8. Drug Enforcement Administration (2015). "Schedules of Controlled Substances: Extension of Temporary Placement of Three Synthetic Phenethylamines in Schedule I. Final order". Fed Regist. 80 (219): 70657–9. PMID 26567439.
9. Drug Enforcement Administration (2015). "Schedules of Controlled Substances: Temporary Placement of Acetyl Fentanyl Into Schedule I. Final order". Fed Regist. 80 (137): 42381–5. PMID 26189217.