Epi-cedrol synthase

Epi-cedrol synthase
Identifiers
EC number 4.2.3.39
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Epi-cedrol synthase (EC 4.2.3.39, 8-epicedrol synthase, epicedrol synthase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (8-epi-cedrol-forming).[1][2] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate + H2O \rightleftharpoons 8-epi-cedrol + diphosphate

This enzyme is activated by Mg2+.

References

  1. Mercke, P., Crock, J., Croteau, R. and Brodelius, P.E. (1999). "Cloning, expression, and characterization of epi-cedrol synthase, a sesquiterpene cyclase from Artemisia annua L". Arch. Biochem. Biophys. 369: 213–222. doi:10.1006/abbi.1999.1358. PMID 10486140.
  2. Hua, L. and Matsuda, S.P. (1999). "The molecular cloning of 8-epicedrol synthase from Artemisia annua". Arch. Biochem. Biophys. 369: 208–212. doi:10.1006/abbi.1999.1357. PMID 10486139.

External links

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