Fludroxycortide

Fludroxycortide
Systematic (IUPAC) name
6-Fluoro-11,21-dihydroxy-16,17-[(l-methylethylidene)bis(oxy)]-(6α,11β,16α)-pregn-4-ene-3,20-dione
Clinical data
Trade names Cordran, Haelan
AHFS/Drugs.com Micromedex Detailed Consumer Information
Routes of
administration
Topical
Legal status
Legal status
  • UK: POM (Prescription only)
Identifiers
CAS Number 1524-88-5 YesY
ATC code D07AC07 (WHO)
PubChem CID 15209
IUPHAR/BPS 7606
DrugBank DB00846 YesY
ChemSpider 14475 YesY
UNII 8EUL29XUQT YesY
KEGG D00328 YesY
ChEMBL CHEMBL1201012 N
Chemical data
Formula C24H33FO6
Molar mass 436.514 g/mol
 NYesY (what is this?)  (verify)

Fludroxycortide (INN, also known as flurandrenolone or flurandrenolide[1]) is a synthetic topical steroid and is used as an anti-inflammatory treatment for use on skin irritations. Trade names include Haelan (Typharm, UK) and Cordran (by Watson Pharmaceuticals, US).[2][3]

Fludroxycortide is available in ointment, cream and as an impregnated tape (Haelan tape, Cordran tape). Licensed indications in the United Kingdom include recalcitrant dermatoses.[4][5]

References

  1. CID 15209 from PubChem
  2. Drugs.com: Fludroxycortide
  3. Patient.info: Fludroxycortide
  4. Haelan Tape Summary of Product Characteristics
  5. Nakamura, H.; Motoyoshi, S.; Ishii, K.; Seto, Y.; Shimizu, M. (1980). "Anti-inflammatory activity of a topical glucocorticoid, fludroxycortide tape in experimental animals (author's transl)". Nihon yakurigaku zasshi. Folia pharmacologica Japonica 76 (7): 595–607. PMID 7215997.



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