GFRA4

GDNF family receptor alpha 4

Identifiers

External IDs

Gene ontology
Molecular function	• glial cell-derived neurotrophic factor receptor activity
Cellular component	• extracellular space • plasma membrane • anchored component of membrane • extracellular exosome
Biological process	• negative regulation of ossification • glial cell-derived neurotrophic factor receptor signaling pathway
Sources: Amigo / QuickGO

Orthologs

Species

Human

Mouse

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 20:
3.66 – 3.66 Mb

Chr 2:
131.04 – 131.04 Mb

PubMed search

GDNF family receptor alpha-4 (GFRα4), also known as the persephin receptor, is a protein that in humans is encoded by the GFRA4 gene.^[1]

References

↑ "Entrez Gene: GFRA4 GDNF family receptor alpha 4".

TrkA	Agonists: Amitriptyline Gambogic amide NGF Tavilermide Antagonists: FX007

TrkB	Agonists: 3,7-DHF 3,7,8,2'-THF 4'-DMA-7,8-DHF 7,3'-DHF 7,8-DHF 7,8,2'-THF 7,8,3'-THF Amitriptyline BDNF Deoxygedunin Diosmetin HIOC LM22A-4 N-Acetylserotonin NT-3 NT-4 Norwogonin (5,7,8-THF) R7 TDP6 Antagonists: ANA-12 Cyclotraxin B Gossypetin (3,5,7,8,3',4'-HHF) Inhibitors: K252a

TrkC	Agonists: NT-3

Others

Antibodies: Tanezumab (against NGF)

Others: Cerebrolysin (neurotrophin mixture)

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GFRA4

See also

References

Further reading