Gamma-humulene synthase
Gamma-humulene synthase (EC 4.2.3.56, humulene cyclase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (gamma-humulene-forming).[1][2] This enzyme catalyses the following chemical reaction
- (2E,6E)-farnesyl diphosphate gamma-humulene + diphosphate
References
- ↑ Steele, C.L., Crock, J., Bohlmann, J. and Croteau, R. (1998). "Sesquiterpene synthases from grand fir (Abies grandis). Comparison of constitutive and wound-induced activities, and cDNA isolation, characterization, and bacterial expression of δ-selinene synthase and γ-humulene synthase". J. Biol. Chem. 273: 2078–2089. doi:10.1074/jbc.273.4.2078. PMID 9442047.
- ↑ Little, D.B. and Croteau, R.B. (2002). "Alteration of product formation by directed mutagenesis and truncation of the multiple-product sesquiterpene synthases δ-selinene synthase and γ-humulene synthase". Arch. Biochem. Biophys. 402 (1): 120–135. doi:10.1016/S0003-9861(02)00068-1. PMID 12051690.
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