Gingipain K

Gingipain K
Identifiers
EC number 3.4.22.47
CAS number 159745-69-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Gingipain K (EC 3.4.22.47, Lys-gingipain, PrtP proteinase) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Endopeptidase with strict specificity for lysyl bonds

Activity of this enzyme is stimulated by glycine.

References

  1. Pike, R., McGraw, W., Potempa, J. and Travis, J. (1994). "Lysine- and arginine-specific proteinases from Porphyromonas gingivalis. Isolation, characterization, and evidence for the existence of complexes with hemagglutinins". J. Biol. Chem. 269: 406–411. PMID 8276827.
  2. Curtis, M.A., Aduse, O.J., Rangarajan, M., Gallagher, A., Sterne, J.A., Reid, C.R., Evans, H.E. and Samuelsson, B. (2002). "Attenuation of the virulence of Porphyromonas gingivalis by using a specific synthetic Kgp protease inhibitor 2". Infect. Immun. 70: 6968–6975. doi:10.1128/iai.70.12.6968-6975.2002. PMID 12438376.

External links

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