Doxercalciferol

Doxercalciferol
Names
IUPAC name
(1S,3R,5Z,7E,22E)-9,10-Secoergosta-5,7,10,22-tetraene-1,3-diol
Other names
1-Hydroxyergocalciferol; 1-Hydroxyvitamin D2; 1α-Hydroxyergocalciferol; 1α-Hydroxyvitamin D2; Hectorol; TSA 840
Identifiers
54573-75-0 YesY
ChEMBL ChEMBL1200810 N
ChemSpider 4444554 YesY
DrugBank DB06410 N
2790
Jmol interactive 3D Image
PubChem 5281107
UNII 3DIZ9LF5Y9 YesY
Properties
C28H44O2
Molar mass 412.66 g·mol−1
Pharmacology
ATC code H05BX03
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Doxercalciferol (trade name Hectorol) is drug for secondary hyperparathyroidism and metabolic bone disease.[1] It is a synthetic analog of ergocalciferol (vitamin D2). It suppresses parathyroid synthesis and secretion.[2]

References

  1. Sprague S M; Ho L T (2002). "Oral doxercalciferol therapy for secondary hyperparathyroidism in a peritoneal dialysis patient". Clinical nephrology 58 (2): 155–160. PMID 12227689.
  2. "Doxercalciferol". Drugs.com.



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