Leucolysin
Leucolysin (EC 3.4.24.6, Leucostoma neutral proteinase, Leucostoma peptidase A) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction
- Cleavage of Phe1-Val, His5-Leu, Ala14-Leu, Gly20-Glu, Gly23-Phe and Phe24-Phe bonds in insulin B chain as well as N-blocked dipeptides
This enzyme is isolated from the venom of the western cottonmouth moccasin snake (Agkistrodon piscivorus leucostoma).
References
- ↑ Wagner, F.W., Spiekerman, A.M. and Prescott, J.M. (1968). "Leucostoma peptidase A. Isolation and physical properties". J. Biol. Chem. 243: 4486–4493. PMID 5684005.
- ↑ Spiekerman, A.M., Fredericks, K.K., Wagner, F.W. and Prescott, J.M. (1973). "Leucostoma peptidase A: a metalloprotease from snake venom". Biochim. Biophys. Acta 293: 464–475. doi:10.1016/0005-2744(73)90353-7. PMID 4711816.
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