| Title | Director | Cast (Subject of documentary) | Genre | Notes |
| .45 | Gary Lennon | Milla Jovovich, Angus Macfadyen, Aisha Tyler, Stephen Dorff | Crime drama | |
| 10 Items or Less | Brad Silberling | Morgan Freeman, Paz Vega | Comedy | |
| 10th & Wolf | Robert Moresco | James Marsden, Giovanni Ribisi | Crime drama | |
| 16 Blocks | Richard Donner | Bruce Willis, Mos Def | Crime drama | |
| 29 Reasons to Run | Damon O'Steen | Gary Weeks | Comedy | |
| The 8th Plague | Franklin Guerrero, Jr. | DJ Perry | Horror | |
| 9/Tenths | Bob Degus | Gabrielle Anwar, Henry Ian Cusick | Romance | |
| a/k/a Tommy Chong | Josh Gilbert | jailing of Tommy Chong | Documentary | |
| Abominable | Ryan Schifrin | Matt McCoy, Jeffrey Combs | Horror | |
| Accepted | Steve Pink | Justin Long, Jonah Hill | Comedy | |
| After... | David L. Cunningham | Daniel Caltagirone | Thriller | |
| Air Guitar Nation | Alexandra Lipsitz | U.S. air guitar championships | Documentary | |
| Akeelah and the Bee | Doug Atchison | Keke Palmer, Laurence Fishburne, Angela Bassett | Family | |
| Al Franken: God Spoke | Nick Doob, Chris Hegedus | emergence of Al Franken as political commentator | Documentary | |
| The Alibi | Matt Checkowski, Kurt Mattila | Steve Coogan, Rebecca Romijn, James Marsden | Romantic comedy | |
| All the King's Men | Steven Zaillian | Sean Penn, Jude Law, Kate Winslet, Anthony Hopkins, Mark Ruffalo, James Gandolfini | Drama | based on All the King's Men by Robert Penn Warren |
| Alone with Her | Eric Nichols | Ana Claudia Talancón, Colin Hanks, Jordana Spiro | Horror | |
| Amazing Grace | Michael Apted | Ioan Gruffudd | Biography | |
| America: Freedom to Fascism | Aaron Russo | the legality of income tax | Documentary | |
| American Blackout | Ian Inaba | 2002 defeat, 2004 reelection of Cynthia McKinney | Documentary | |
| American Dreamz | Paul Weitz | Hugh Grant, Dennis Quaid, Mandy Moore, Marcia Gay Harden | Comedy, parody | |
| American Hardcore | Paul Rachman | early pioneers of the hardcore punk music scene | Documentary | based on American Hardcore: A Tribal History by Steven Blush |
| Analog Days | Mike Ott | Chad Cunningham | Drama | |
| Andy Warhol: A Documentary Film | Ric Burns | life and art of Andy Warhol | Documentary | |
| Annapolis | Justin Lin | James Franco, Tyrese Gibson | Drama | |
| Another Gay Movie | Todd Stephens | Michael Carbonaro, Jonah Blechman, Jonathan Chase, Mitch Morris | Comedy | |
| The Ant Bully | John A. Davis | Julia Roberts, Nicolas Cage, Meryl Streep, Paul Giamatti | Animation | based on The Ant Bully by John Nickle |
| Apocalypto | Mel Gibson | Rudy Youngblood, Raoul Trujillo, Mayra Sérbulo, Dalia Hernández | Action | |
| Aquamarine | Elizabeth Allen | Emma Roberts, Sara Paxton, JoJo | Fantasy, teen | |
| The Architect | Matt Tauber | Anthony LaPaglia, Viola Davis, Isabella Rossellini | Drama | |
| Art School Confidential | Terry Zwigoff | Max Minghella, Sophia Myles, John Malkovich | Comedy-drama | based on "Art School Confidential" by Daniel Clowes |
| Artie Lange's Beer League | Frank Sebastiano | Artie Lange, Ralph Macchio | Comedy | |
| As You Like It | Kenneth Branagh | Kevin Kline, Bryce Dallas Howard, Alfred Molina | Comedy-drama | based on As You Like It by William Shakespeare |
| Asian Stories | Ron Oda, Kris Chin | James Kyson Lee, Kirt Kishita | Comedy-drama | |
| Ask the Dust | Robert Towne | Colin Farrell, Salma Hayek | Drama | based on Ask the Dust by John Fante |
| The Astronaut Farmer | Michael Polish | Billy Bob Thornton, Virginia Madsen, Bruce Dern, Bruce Willis | Drama | |
| ATL | Chris Robinson | T.I., Lauren London, Evan Ross, Big Boi | Comedy-drama | |
| Automaton Transfusion | Steven C. Miller | Garrett Jones | Horror | |
| Automatons | James Felix McKenney | Angus Scrimm | Science fiction | |
| Awesome; I Fuckin' Shot That! | Nathaniel Hörnblowér | Beastie Boys | Concert | |
| Babel | Alejandro González Iñárritu | Brad Pitt, Cate Blanchett, Gael García Bernal, Kōji Yakusho | Drama | winner Golden Globe Award for Best Motion Picture – Drama |
| Bambi II | Brian Pimental | Alexander Gould, Patrick Stewart, Brendon Baerg | Animation | preceded by Bambi; direct-to-video |
| Barnyard | Steve Oedekerk | Kevin James, Courteney Cox, Sam Elliott, Danny Glover | Animation | |
| Basic Instinct 2 | Michael Caton-Jones | Sharon Stone, David Morrissey, David Thewlis, Charlotte Rampling | Thriller | preceded by Basic Instinct |
| The Beach Party at the Threshold of Hell | Kevin Wheatley, Jonny Gilette | Kevin Wheatley, Bill English | Comedy | |
| Beerfest | Jay Chandrasekhar | Paul Soter, Erik Stolhanske | Comedy | |
| Behind the Mask: The Rise of Leslie Vernon | Scott Glosserman | Nathan Baesel, Robert Englund, Angela Goethals | Mockumentary | |
| Bella | Alejandro Gomez Monteverde | Eduardo Verástegui, Tammy Blanchard, Manny Pérez | Drama | |
| The Benchwarmers | Dennis Dugan | Rob Schneider, David Spade, Jon Heder | Comedy | |
| Beyond Conviction | Rachel Libert | the healing and resolution of three crime victims | Documentary | |
| Bickford Shmeckler's Cool Ideas | Scott Lew | Patrick Fugit, Olivia Wilde, Fran Kranz, John Cho | Comedy | |
| The Big Bad Swim | Ishai Setton | Paget Brewster, Jeff Branson, Jess Weixler | Comedy | |
| Big Bad Wolf | Lance W. Dreesen | Kimberly J. Brown, Trevor Duke, Sarah Christine Smith | Horror | |
| Big Dreams Little Tokyo | David Boyle | David Boyd | Comedy | |
| Big Momma's House 2 | John Whitesell | Martin Lawrence | Comedy | preceded by Big Momma's House |
| Black Christmas | Glen Morgan | Katie Cassidy, Michelle Trachtenberg, Kristen Cloke, Crystal Lowe | Horror | based on Black Christman |
| The Black Dahlia | Brian De Palma | Josh Hartnett, Scarlett Johansson, Aaron Eckhart, Hilary Swank | Crime drama | based on The Black Dahlia by James Ellroy |
| Black Gold | Mark Francis, Nick Francis | international coffee trade | Documentary | |
| Blind Dating | James Keach | Chris Pine, Eddie Kaye Thomas, Anjali Jay | Comedy | |
| Blood Diamond | Edward Zwick | Leonardo DiCaprio, Jennifer Connelly, Djimon Hounsou | Drama | |
| Blood Tea and Red String | Christiane Cegavske | | Animation | |
| Bloody Mary | Richard Valentine | Jaason Simmons, Kim Tyler, Matt Borlenghi | Horror | |
| Bobby | Emilio Estevez | Harry Belafonte, Joy Bryant, Nick Cannon, Laurence Fishburne, Anthony Hopkins, Helen Hunt, Ashton Kutcher, Shia LaBeouf, Lindsay Lohan, Demi Moore, Christian Slater, Martin Sheen, Sharon Stone | Drama | |
| Borat! Cultural Learnings of America for Make Benefit Glorious Nation of Kazakhstan | Larry Charles | Sacha Baron Cohen, Ken Davitian, Luenell | Mockumentary | |
| Bordertown | Gregory Nava | Jennifer Lopez, Antonio Banderas | Crime drama | |
| Brand Upon the Brain! | Guy Maddin | Sullivan Brown, Gretchen Krich, Maya Lawson, Erik Steffen Maahs | Drama, silent | |
| Breaking and Entering | Anthony Minghella | Jude Law, Juliette Binoche, Robni Wright Penn | Romance | |
| The Break-Up | Peyton Reed | Vince Vaughn, Jennifer Aniston | Romance | |
| The Breed | Nicholas Mastandrea | Michelle Rodriguez, Eric Lively, Oliver Hudson | Horror | |
| The Bridge | Eric Steel | suicide at Golden Gate Bridge | Documentary | |
| Broken Bridges | Steven Goldmann | Toby Keith, Kelly Preston, Willie Nelson, Lindsey Haun | Musical | |
| Busgirl | Steven Schuldt | Leah Miller | Drama | |
| Caffeine | John Cosgrove | Mena Suvari, Marsha Thomason, Katherine Heigl | Comedy | |
| Cars | Joe Ranft, John Lasseter | Paul Newman, Owen Wilson, Larry the Cable Guy, Tony Shalhoub, Bonnie Hunt | Animation | winner of Golden Globe Award for Best Animated Feature Film |
| Casino Royale | Martin Campbell | Daniel Craig, Eva Green, Mads Mikkelsen, Judi Dench, Giancarlo Giannini, Jeffrey Wright | Action, 007 | preceded by Die Another Day |
| Catch a Fire | Phillip Noyce | Tim Robbins, Derek Luke | Drama | |
| The Cats of Mirikitani | Linda Hattendorf | the life of Japanese American painter Jimmy Mirikitani | Documentary | |
| Chalk | Mike Akel | Chris Mass | Mockumentary | |
| Charlotte's Web | Gary Winick | Dakota Fanning, Dominic Scott Kay, Julia Roberts, Steve Buscemi | Family | based on Charlotte's Web by E. B. White |
| Chasing the Horizon | Markus and Mason Canter | the Baja 1000 off-road race | Documentary | |
| Children of Men | Alfonso Cuarón | Clive Owen, Julianne Moore | Science fiction | based on The Children of Men by P. D. James |
| Christmas at Maxwell's | William C. Laufer | Andrew May, Jack Hourigan | Drama | |
| Church Ball | Kurt Hale | Fred Willard, Andrew Wilson, Clint Howard | Comedy | |
| Civic Duty | Jeff Renfroe | Peter Krause, Khaled Abol Naga, Richard Schiff | Drama | |
| Clear Cut: The Story of Philomath, Oregon | Peter Richardson | timber industry in Philomath, Oregon | Documentary | |
| Clerks II | Kevin Smith | Brian O'Halloran, Jeff Anderson, Rosario Dawson, Jason Mewes, Kevin Smith, Trevor Fehrman | Comedy | preceded by Clerks |
| Click | Frank Coraci | Adam Sandler, Kate Beckinsale, Christopher Walken, David Hasselhoff | Comedy | |
| Cocaine Cowboys | Billy Corben | cocaine in Miami during 1970s and 1980s | Documentary | |
| Coffee Date | Stewart Wade | Jonathan Bray, Wilson Cruz | Comedy | |
| Color of the Cross | Jean-Claude La Marre | Jean-Claude La Marre, Debbi Morgan, Elya Baskin | Biography | |
| Come Early Morning | Joey Lauren Adams | Ashley Judd, Jeffrey Donovan, Ray McKinnon | Drama | |
| The Contract | Bruce Beresford | Morgan Freeman, John Cusack | Drama | |
| Copying Beethoven | Agnieszka Holland | Ed Harris, Diane Kruger | Drama | |
| The Covenant | Renny Harlin | Steven Strait, Sebastian Stan, Laura Ramsey, Taylor Kitsch | Horror | |
| Crank | Mark Neveldine, Brian Taylor | Jason Statham, Amy Smart | Action | |
| Crossover | Preston A. Whitmore II | Anthony Mackie, Wesley Jonathan, Wayne Brady, Lil' JJ | Action | |
| Crude Impact | James Jandak Wood | the effect of fossil fuels | Documentary | |
| Curious George | Matthew O'Callaghan | Will Ferrell, Drew Barrymore, David Cross, Eugene Levy | Animation | based on the Curious George by H. A. and Margret Rey |
| The Curiosity of Chance | Russell P. Marleau | Tad Hilgenbrink, Brett Chukerman | Comedy | |
| The Da Vinci Code | Ron Howard | Tom Hanks, Audrey Tautou, Ian McKellen, Alfred Molina, Paul Bettany, Jean Reno, Jürgen Prochnow | Thriller | based on The Da Vinci Code by Dan Brown |
| Daft Punk's Electroma | Daft Punk | Peter Hurteau, Michael Reich | Science fiction | |
| Dance Party USA | Aaron Katz | Cole Pensinger, Anna Kavan, Ryan White | Drama | |
| Danika | Ariel Vromen | Marisa Tomei, Regina Hall, Craig Bierko | Horror | |
| Danny Roane: First Time Director | Andy Dick | Andy Dick, Frankie Muniz, Jack Black | Comedy | |
| Dark Corners | Ray Gower | Thora Birch, Toby Stephens, Christien Anholt | Horror | |
| Dark Ride | Craig Singer | Jamie-Lynn Sigler, Patrick Renna, Jennifer Tisdale | Horror | |
| The Darwin Awards | Finn Taylor | Joseph Fiennes, Winona Ryder, David Arquette | Comedy | based on Darwin Awards |
| Date Movie | Aaron Seltzer | Alyson Hannigan, Adam Campbell, Jennifer Coolidge, Tony Cox | Romantic comedy | |
| Dave Chappelle's Block Party | Michel Gondry | a block party held in Clinton Hill, Brooklyn by Dave Chappelle | Comedy | based on Wattstax |
| Day Night Day Night | Julia Loktev | Luisa Williams | Drama | |
| Day on Fire | Jay Anania | Olympia Dukakis, Carmen Chaplin, Martin Donovan | Drama | |
| The Dead Girl | Karen Moncrieff | Toni Collette, Brittany Murphy | Drama | |
| The Death of Poe | Mark Redfield | Mark Redfield, Kevin G. Shinnick | Horror | |
| Déjà Vu | Tony Scott | Denzel Washington, Val Kilmer | Science fiction | |
| Deck the Halls | John Whitesell | Danny DeVito, Matthew Broderick, Kristin Davis, Kristin Chenoweth | Comedy | |
| Deliver Us from Evil | Amy Berg | the life of Oliver O'Grady | Documentary | winner of the Satellite Award for Best Documentary Film |
| The Departed | Martin Scorsese | Leonardo DiCaprio, Matt Damon, Jack Nicholson, Mark Wahlberg, Alec Baldwin, Martin Sheen, Vera Farmiga, Anthony Anderson, Ray Winstone | Crime drama | based on Infernal Affairs
Academy Award for Best Picture and Satellite Award for Best Film – Drama |
| The Devil and Daniel Johnston | Jeff Feuerzeig | life and music of Daniel Johnston | Documentary | |
| The Devil Wears Prada | David Frankel | Meryl Streep, Anne Hathaway, Emily Blunt, Stanley Tucci, Adrian Grenier, Simon Baker | Comedy, Drama | based on The Devil Wears Prada by Lauren Weisberger |
| Diggers | Katherine Dieckmann | Paul Rudd, Lauren Ambrose, Ron Eldard | Comedy | |
| Disappearances | Jay Craven | Kris Kristofferson | Drama | |
| Dixie Chicks: Shut Up and Sing | Cecilia Peck, Barbara Kopple | the career of the Dixie Chicks | Documentary | |
| DOA: Dead or Alive | Corey Yuen | Jaime Pressly, Holly Valance, Sarah Carter, Natassia Malthe, Devon Aoki, Eric Roberts | Action | based on Dead or Alive series |
| The Dog Problem | Scott Caan | Giovanni Ribisi, Lynn Collins, Kevin Corrigan | Comedy | |
| Dreamgirls | Bill Condon | Jamie Foxx, Beyoncé Knowles, Eddie Murphy, Jennifer Hudson, Anika Noni Rose | Musical | Golden Globe Award for Best Motion Picture – Musical or Comedy and Satellite Award for Best Film – Musical or Comedy |
| Dreamland | Jason Matzner | Agnes Bruckner, Kelli Garner, Justin Long | Drama | |
| Driftwood | Tim Sullivan | Raviv Ullman, Diamond Dallas Page, Talan Torriero | Horror | |
| Disaster Zone: Volcano in New York | Robert Zemeckis | Costas Mandylor, Alexandra Paul, Michael Ironside | Disaster | |
| East Side Story | Carlos Portugal | René Alvarado, Steve Callahan | Comedy | |
| Employee of the Month | Gregory Coolidge | Dane Cook, Jessica Simpson, Dax Shepard | Comedy | |
| Encounter Point | Ronit Avni, Julia Bacha | violence in Israel between Israelis and Palestinians | Documentary | |
| End Game | Andy Cheng | Cuba Gooding, Jr., James Woods, Angie Harmon | Action | |
| End of the Spear | Jim Hanon | Louie Leonardo, Chad Allen, Jack Guzman | Drama | |
| Eight Below | Frank Marshall | Paul Walker, Bruce Greenwood | Adventure | based on Nankyoku Monogatari |
| Eragon | Stefen Fangmeier | Ed Speleers, Jeremy Irons, Sienna Guillory, Robert Carlyle, John Malkovich | Fantasy | based on Eragon by Christopher Paolini |
| Everyone's Hero | Christopher Reeve, Daniel St. Pierre, Colin Brady | Jake T. Austin, Rob Reiner, William H. Macy | Animation | |
| Evil Bong | Charles Band | David Weidoff | Comedy | |
| Expiration Date | Rick Stevenson | Rober Guthrie | Comedy | |
| Facing the Giants | Alex Kendrick | Alex Kendrick, Shannen Fields, Tracy Goode | Drama | |
| Factory Girl | George Hickenlooper | Sienna Miller, Hayden Christensen, Jimmy Fallon | Biography | |
| Failure to Launch | Tom Dey | Matthew McConaughey, Sarah Jessica Parker, Terry Bradshaw, Kathy Bates | Romantic comedy | |
| The Fast and the Furious: Tokyo Drift | Justin Lin | Lucas Black, Bow Wow | Action | preceded by 2 Fast 2 Furious |
| Fast Food Nation | Richard Linklater | Greg Kinnear, Wilmer Valderrama, Avril Lavigne | Drama | based on Fast Food Nation by Eric Schlosser |
| Fatwa | John Carter | Lauren Holly, Lacey Chabert, John Doman | Drama | |
| Fay Grim | Hal Hartley | Parker Posey, James Urbaniak, Liam Aiken | Action | |
| Fearless | Ronny Yu | Jet Li | Martial arts | |
| Fifty Pills | Theo Avgerinos | Lou Taylor Pucci, Kristen Bell, John Hensley | Comedy | |
| Final Destination 3 | James Wong | Mary Elizabeth Winstead, Ryan Merriman, Kris Lemche, Texas Battle | Horror | preceded by Final Destination 2 |
| Find Me Guilty | Sidney Lumet | Vin Diesel, Linus Roache, Ron Silver, Alex Rocco, Peter Dinklage, Annabella Sciorra | Crime drama | based on life of mobster Jackie DiNorscio |
| Firewall | Richard Loncraine | Harrison Ford, Paul Bettany, Virginia Madsen, Mary Lynn Rajskub | Thriller | |
| Flags of Our Fathers | Clint Eastwood | Ryan Phillippe, Jesse Bradford, Adam Beach | War | based on Flags of Our Fathers by James Bradley and Ron Powers |
| Flicka | Michael Mayer | Alison Lohman, Tim McGraw, Maria Bello | Family | based on My Friend Flicka by Mary O'Hara |
| Flock of Dodos | Randy Olson | the debate between intelligent design and evolution | Documentary | |
| Flourish | Kevin Palys | Jennifer Morrison, Jesse Spencer, Leighton Meester | Comedy-drama | |
| Flushed Away | David Bowers, Sam Fell | Kate Winslet, Hugh Jackman, Ian McKellen, Andy Serkis | Animation | |
| Flyboys | Tony Bill | James Franco, Martin Henderson, Jean Reno | War | |
| For Your Consideration | Christopher Guest | Catherine O'Hara, Parker Posey, Harry Shearer, Eugene Levy, Fred Willard, Jane Lynch | Comedy | |
| Forget About It | BJ Davis | Burt Reynolds, Robert Loggia, Charles Durning | Comedy-drama | |
| The Fountain | Darren Aronofsky | Hugh Jackman, Rachel Weisz, Ellen Burstyn | Science fiction | |
| Freedomland | Joe Roth | Samuel L. Jackson, Julianne Moore | Crime drama | based on Freedomland by Richard Price |
| Free Jimmy | Christopher Nielsen | Jeremy Price, Woody Harrelson, Simon Pegg, Phil Daniels | Animation | |
| Friends with Money | Nicole Holofcener | Jennifer Aniston, Joan Cusack, Catherine Keener, Frances McDormand | Drama | |
| Full Grown Men | David Munro | Matt McGrath, Judah Friedlander, Alan Cumming | Comedy | |
| Fur | Steven Shainberg | Nicole Kidman, Robert Downey, Jr. | Drama | |
| Game 6 | Michael Hoffman | Michael Keaton, Griffin Dunne, Robert Downey, Jr. | Comedy | |
| Garfield: A Tail of Two Kitties | Tim Hill | Breckin Meyer, Jennifer Love Hewitt, Billy Connolly, Bill Murray | Comedy | preceded by Garfield: The Movie |
| The Genius Club | Tim Chey | Stephen Baldwin, Tom Sizemore, Jack Scalia | Drama | |
| GI Jesus | Carl Colpaert | Joe Arquette | Fantasy | |
| Glastonbury | Julien Temple | history of Glastonbury Festival | Documentary | |
| Glory Road | James Gartner | Josh Lucas, Derek Luke, Jon Voight | Drama | |
| God Grew Tired of Us | Christopher Dillon Quinn | the Lost Boys of Sudan | Documentary | winner of Sundance Grand Jury Prize |
| The Good German | Steven Soderbergh | George Clooney, Cate Blanchett, Tobey Maguire | Drama, War | based on The Good German by Joseph Kanon |
| The Good Shepherd | Robert De Niro | Matt Damon, Angelina Jolie, Robert De Niro, Alec Baldwin, William Hurt, Michael Gambon, Timothy Hutton | Drama | |
| A Good Year | Ridley Scott | Russell Crowe | Drama | based on A Good Year by Peter Mayle |
| Goya's Ghosts | Miloš Forman | Natalie Portman, Javier Bardem, Stellan Skarsgård | Drama | |
| Grandma's Boy | Nicholaus Goossen | Linda Cardellini, Allen Covert, Peter Dante, Doris Roberts, Shirley Jones | Comedy | |
| The Great Warming | Michael Taylor | climate change | Documentary | |
| Gridiron Gang | Phil Joanou | Dwayne Johnson | Drama | |
| The Groomsmen | Edward Burns | Edward Burns, John Leguizamo, Matthew Lillard, Donal Logue | Comedy | |
| The Grudge 2 | Takashi Shimizu | Sarah Michelle Gellar, Amber Tamblyn | Horror | preceded by The Grudge |
| The Guardian | Andrew Davis | Kevin Costner, Ashton Kutcher | Drama | |
| The Guatemalan Handshake | Todd Rohal | Katy Haywood | Comedy-drama | |
| A Guide to Recognizing Your Saints | Dito Montiel | Robert Downey, Jr., Shia LaBeouf, Chazz Palminteri, Dianne Wiest | Crime drama | |
| Half Nelson | Ryan Fleck | Ryan Gosling, Shareeka Epps | Drama | |
| The Hamiltons | Butcher brothers | Cory Knauf, Samuel Child, Joseph McKelheer | Horror | |
| Happy Feet | George Miller, Warren Coleman, Judy Morris | Elijah Wood, Robin Williams, Brittany Murphy, Hugh Jackman | Animation, Musical | winner of Academy Award for Best Animated Feature, BAFTA Award for Best Animated Film |
| The Hard Corps | Sheldon Lettich | Jean-Claude Van Damme, Vivica A. Fox, Razaaq Adoti | Action | |
| Harsh Times | David Ayer | Christian Bale, Freddy Rodríguez, Eva Longoria | Crime drama | |
| The Hawk Is Dying | Julian Goldberger | Paul Giamatti, Michelle Williams | Drama | based on The Hawk Is Dying by Harry Crews |
| Header | Archibald Flancranstin | Jake Suffian | Horror | based on "Header" by Edward Lee |
| The Heart of Steel | Angelo J. Guglielmo, Jr. | aftermath of September 11 attacks | Documentary | |
| The Heart of the Game | Ward Serrill | the Roosevelt Roughriders girls basketball team | Documentary | |
| The Hills Have Eyes | Alexandre Aja | Aaron Stanford, Emilie de Ravin, Ted Levine, Dan Byrd | Horror | based on The Hills Have Eyes |
| Hip-Hop: Beyond Beats and Rhymes | Byron Hurt | violence, homophobia and sexism in hip hop | Documentary | |
| The Holiday | Nancy Meyers | Cameron Diaz, Kate Winslet, Jude Law, Jack Black | Romance | |
| Hollywoodland | Allen Coulter | Adrien Brody, Diane Lane, Ben Affleck | Biography, Crime | based on life of actor George Reeves |
| Hollow Man 2 | Claudio Fäh | Christian Slater, Peter Facinelli, Laura Regan | Science fiction | Direct-to-video |
| Home of the Brave | Irwin Winkler | Samuel L. Jackson, Jessica Biel, Brian Presley, 50 Cent | Drama | based on The Best Years of Our Lives |
|
| Hood of Horror | Stacy Title | Snoop Dogg, Ernie Hudson, Danny Trejo | Horror | |
| Hoot | Wil Shriner | Luke Wilson, Brie Larson, Logan Lerman, Cody Linley | Family | based on Hoot by Carl Hiaasen |
| The Hottest State | Ethan Hawke | Mark Webber, Catalina Sandino Moreno, Michelle Williams | Drama | based on The Hottest State by Ethan Hawke |
| How to Eat Fried Worms | Bob Dolman | Luke Benward, Adam Hicks | Comedy | based on How to Eat Fried Worms by Thomas Rockwell |
| Hurricane on the Bayou | Greg MacGillivray | wetlands of Louisiana and Hurricane Katrina | Documentary | |
| I Want Someone to Eat Cheese With | Jeff Garlin | Jeff Garlin, Sarah Silverman, Bonnie Hunt | Comedy | |
| Ice Age: The Meltdown | Carlos Saldanha | Ray Romano, John Leguizamo, Denis Leary, Queen Latifah | Animation | preceded by Ice Age |
| Idiocracy | Mike Judge | Luke Wilson, Maya Rudolph | Comedy, Science fiction | |
| Idlewild | Bryan Barber | André Benjamin, Big Boi | Crime | |
| The Illusionist | Neil Burger | Edward Norton, Paul Giamatti, Jessica Biel | Drama | based on "Eisenheim the Illusionist" by Steven Millhauser |
| An Inconvenient Truth | Davis Guggenheim | global warming | Documentary | winner of Academy Award for Best Documentary Feature |
| Infamous | Douglas McGrath | Toby Jones, Sandra Bullock, Daniel Craig, Lee Pace, Jeff Daniels, Hope Davis, Sigourney Weaver | Biography, Crime | based on Capote: In Which Various Friends, Enemies, Acquaintances and Detractors Recall His Turbulent Career by George Plimpton |
| Inland Empire | David Lynch | Laura Dern, Jeremy Irons, Justin Theroux, Harry Dean Stanton | Drama | |
| Inside Man | Spike Lee | Denzel Washington, Clive Owen, Jodie Foster | Crime drama | |
| The Insurgents | Scott Dacko | John Shea, Mary Stuart Masterson, Juliette Marquis | Drama | |
| Invincible | Ericson Core | Mark Wahlberg, Elizabeth Banks | Biography | |
| Interkosmos | Jim Finn | Dean DeMatteis | Drama | |
| Iraq for Sale: The War Profiteers | Robert Greenwald | Iraq War companies with no-bid contracts | Documentary | |
| Iraq in Fragments | James Longley | the effects of the Iraq War on Iraq | Documentary | |
| Irish Jam | John Eyres | Eddie Griffin | Comedy | |
| Jackass Number Two | Jeff Tremaine | Johnny Knoxville, Steve-O, Bam Margera, Chris Pontius | Comedy, reality | preceded by Jackass: The Movie |
| Jack Smith and the Destruction of Atlantis | Mary Jordan | life of director Jack Smith | Documentary | |
| Jesus Camp | Heidi Ewing, Rachel Grady | a Pentecostal–Charismatic Christian summer camp | Documentary | |
| Jewish American Princess | Jacqueline Davis, Ian Davis | search for perfect Jewish man | Documentary | |
| Jimmy and Judy | Randall Rubin, Jon Schroder | Edward Furlong, Rachael Bella | Crime drama | |
| John Tucker Must Die | Betty Thomas | Jesse Metcalfe, Brittany Snow, Ashanti, Sophia Bush, Arielle Kebbel, Jenny McCarthy | Comedy | |
| Jonestown: The Life and Death of Peoples Temple | Stanley Nelson | mass suicide of Peoples Temple and leader Jim Jones | Documentary | |
| Just My Luck | Donald Petrie | Lindsay Lohan, Chris Pine | Comedy | |
| Kalamazoo? | David O'Malley | Josie Davis, Mayim Bialik | Comedy | |
| Karla | Joel Bender | Laura Prepon, Misha Collins | Drama | |
| Keeping Up with the Steins | Scott Marshall | Daryl Sabara, Jami Gertz, Jeremy Piven | Comedy | |
| Kill Your Darlings | Björne Larson | Lolita Davidovich, Andreas Wilson, Fares Fares | Comedy | |
| Kurt Cobain About a Son | AJ Schnack | life and music of Kurt Cobain | Documentary | |
| Lady in the Water | M. Night Shyamalan | Paul Giamatti, Bryce Dallas Howard | Thriller | |
| The Lake House | Alejandro Agresti | Keanu Reeves, Sandra Bullock | Romance | based on Il Mare |
| Land of the Blind | Robert Edwards | Donald Sutherland, Ralph Fiennes | Drama | |
| Larry the Cable Guy: Health Inspector | Trent Cooper | Larry the Cable Guy, Iris Bahr, Bruce Bruce | Comedy | |
| The Last Kiss | Tony Goldwyn | Zach Braff, Jacinda Barrett, Rachel Bilson | Drama | based on L'ultimo bacio |
| Last Holiday | Wayne Wang | Queen Latifah, LL Cool J, Timothy Hutton, Gérard Depardieu | Romance | based on Last Holiday |
| The Last Winter | Larry Fessenden | Ron Perlman, James LeGros, Connie Britton | Horror | |
| The Legend of Simon Conjurer | Q. Mark | Jon Voight | Action | |
| Let's Go to Prison | Bob Odenkirk | Will Arnett, Dax Shepard, Chi McBride | Comedy | based on You Are Going to Prison by Jim Hogshire |
| Letters from Iwo Jima | Clint Eastwood | Ken Watanabe, Kazunari Ninomiya, Tsuyoshi Ihara, Ryō Kase | War | preceded by Flags of Our Fathers
Golden Globe Award for Best Foreign Language Film |
| Lime Salted Love | Danielle Agnello, Joe Hall | Kristanna Loken | Drama | |
| Little Chenier | Bethany Ashton | Johnathon Schaech, Frederick Koehler, Tamara Braun | Drama | |
| Little Children | Todd Field | Kate Winslet, Patrick Wilson, Jennifer Connelly, Jackie Earle Haley | Drama | based on Little Children by Tom Perrotta |
| Little Man | Keenen Ivory Wayans | Marlon Wayans, Shawn Wayans, Kerry Washington | Comedy | |
| Little Miss Sunshine | Jonathan Dayton and Valerie Faris | Greg Kinnear, Steve Carell, Toni Collette, Paul Dano, Abigail Breslin, Alan Arkin | Comedy-drama | Academy Award for Arkin |
| Live Freaky! Die Freaky! | John Roecker | Jason Schmidt, Tim Armstrong | Animation | |
| Live Free or Die | Gregg Kavet, Andy Robin | Aaron Stanford, Paul Schneider, Michael Rapaport | Comedy | |
| Local Color | George Gallo | Armin Mueller-Stahl, Trevor Morgan, Ray Liotta | Drama | |
| LOL | Joe Swanberg | Kevin Bewersdorf, Joe Swanberg | Comedy-drama | |
| Lonely Hearts | Todd Robinson | John Travolta, Salma Hayek, Jared Leto, James Gandolfini | Crime drama | |
| The Long Weekend | Pat Holden | Chris Klein, Brendan Fehr | Comedy | |
| Loren Cass | Chris Fuller | Kayla Tabish, Travis Maynard, Lewis Brogan | Drama | |
| Loving Annabelle | Katherine Brooks | Diane Gaidry, Erin Kelly | Drama | based on Mädchen in Uniform |
| Lucky Number Slevin | Paul McGuigan | Josh Hartnett, Morgan Freeman, Ben Kingsley, Lucy Liu, Stanley Tucci, Bruce Willis | Crime drama | |
| Mad Cowgirl | Gregory Hatanaka | Sarah Lassez, James Duval, Walter Koenig | Drama | |
| Madea's Family Reunion | Tyler Perry | Tyler Perry, Blair Underwood, Lynn Whitfield, Boris Kodjoe | Comedy-drama | based on Madea's Family Reunion by Tyler Perry
preceded by Diary of a Mad Black Woman |
| Man About Town | Mike Binder | Ben Affleck, Rebecca Romijn, John Cleese, Jerry O'Connell, Gina Gershon, Bai Ling | Comedy | |
| Man of the Year | Barry Levinson | Robin Williams, Laura Linney | Comedy | |
| Marie Antoinette | Sofia Coppola | Kirsten Dunst, Jason Schwartzman, Judy Davis | Biography | based on Marie Antoinette: The Journey by Antonia Fraser |
| The Marine | John Bonito | John Cena, Kelly Carlson, Robert Patrick | Action | |
| Mark of the Damned | Eric Miller | | Horror | |
| Material Girls | Martha Coolidge | Hilary Duff, Haylie Duff, Anjelica Huston | Comedy | |
| Matthew Barney: No Restraint | Alison Chernick | filmmaking process of Matthew Barney, Björk | Documentary | |
| Maxed Out | James Scurlock | the credit card industry | Documentary | |
| Miami Vice | Michael Mann | Jamie Foxx, Colin Farrell, Gong Li | Action | based on Miami Vice |
| Mini's First Time | Nick Guthe | Alec Baldwin, Nikki Reed, Luke Wilson | Comedy-drama | |
| Minotaur | Jonathan English | Tom Hardy, Tony Todd, Rutger Hauer | Horror | |
| Miss Potter | Chris Noonan | Renée Zellweger, Ewan McGregor, Emily Watson | Biography | based on life of Beatrix Potter |
| Modern Man | Justin Swibel | Eric Becker | Drama | |
| Monster House | Gil Kenan | Mitchel Musso, Sam Lerner, Spencer Locke, Steve Buscemi | Animation | |
| The Monster of Phantom Lake | Christopher R. Mihm | Josh Craig | Horror comedy | |
| Moonshine | Roger Ingraham | Brian Greer | Horror comedy | |
| Mustang Sally | Iren Koster | Elizabeth Daily, Mark Anthony Parrish | Horror | |
| My Country, My Country | Laura Poitras | the life of Iraqis under American occupation | Documentary | |
| Mission: Impossible III | J. J. Abrams | Tom Cruise, Jonathan Rhys Meyers, Philip Seymour Hoffman, Ving Rhames | Action, spy | preceded by Mission: Impossible II |
| My Super Ex-Girlfriend | Ivan Reitman | Uma Thurman, Luke Wilson, Anna Faris | Superhero | |
| Nacho Libre | Jared and Jerusha Hess | Jack Black | Comedy | |
| National Lampoon's Van Wilder: The Rise of Taj | Mort Nathan | Kal Penn, Glen Barry, Lauren Cohan | Comedy | preceded by National Lampoon's Van Wilder |
| The Nativity Story | Catherine Hardwicke | Keisha Castle-Hughes, Shohreh Aghdashloo | Family | based on the Nativity of Jesus |
| Neil Young: Heart of Gold | Jonathan Demme | Neil Young | Concert | |
| Night at the Museum | Shawn Levy | Ben Stiller, Robin Williams, Owen Wilson, Dick Van Dyke, Mickey Rooney, Carla Gugino, Jake Cherry | Fantasy | based on The Night at the Museum by Milan Trenc |
| The Night Listener | Patrick Stettner | Robin Williams, Toni Collette, Bobby Cannavale, Sandra Oh | Thriller | based on The Night Listener by Armistead Maupin |
| Night of the Living Dead 3D | Jeff Broadstreet | Brianna Brown | Horror | based on Night of the Living Dead |
| The Night of the White Pants | Amy Talkington | Tom Wilkinson, Selma Blair, Nick Stahl | Comedy-drama | |
| Nightmare Man | Rolfe Kanefsky | Gwen Davis | Horror | |
| No Limit | Brian O'Hare, Timothy Rhys | the professional poker tournament circuit | Documentary | |
| O Jerusalem | Élie Chouraqui | JJ Feild, Saïd Taghmaoui | Drama | |
| Occupation 101 | Sufyan and Abdallah Omeish | the Israeli–Palestinian conflict | Documentary | |
| The Oh in Ohio | Billy Kent | Parker Posey, Paul Rudd, Danny DeVito, Mischa Barton | Comedy | |
| Old Joy | Kelly Reichardt | Will Oldham, Daniel London | Drama | based on "Old Joy" by Jonathan Raymond |
| The Omen | John Moore | Liev Schreiber, Julia Stiles, Seamus Davey-Fitzpatrick, David Thewlis, Mia Farrow | Horror | based on The Omen |
| Once in a Lifetime: The Extraordinary Story of the New York Cosmos | Paul Crowder, John Dower | Matt Dillon (narrator), Pelé, Giorgio Chinaglia | Documentary | the New York Cosmos |
| One Night with the King | Michael O. Sajbel | Tiffany Dupont | Drama | based on Hadassah: One Night with the King by Tommy Tenney, Mark Andrew Olsen |
| The One Percent | Jamie Johnson | America's growing wealth gap | Documentary | |
| Open Season | Roger Allers, Jill Culton, Anthony Stacchi | Martin Lawrence, Ashton Kutcher, Debra Messing, Gary Sinise | Animation | |
| Over the Hedge | Karey Kirkpatrick, Tim Johnson | Bruce Willis, Garry Shandling, Steve Carell, Wanda Sykes, Nick Nolte | Animation | |
| The Painted Veil | John Curran | Naomi Watts, Edward Norton | Drama | based on The Painted Veil by W. Somerset Maugham |
| Pan's Labyrinth | Guillermo del Toro | Ivana Baquero, Doug Jones, Sergi López | Fantasy | winner of Satellite Award for Best Animated or Mixed Media Feature |
| Paper Dolls | Tomer Heymann | transgender migrant workers from Philippines | Documentary | |
| Park | Kurt Voekler | William Baldwin, Ricki Lake, Cheri Oteri | Comedy-drama | |
| Peaceful Warrior | Victor Salva | Scott Mechlowicz, Nick Nolte, Amy Smart | Drama | based on Way of the Peaceful Warrior by Dan Millman |
| Penelope | Mark Palansky | Christina Ricci, James McAvoy, Catherine O'Hara, Reese Witherspoon | Romantic comedy | |
| Perfume: The Story of a Murderer | Tom Tykwer | Ben Whishaw, Dustin Hoffman, Alan Rickman | Crime drama | based on Perfume by Patrick Süskind |
| Phat Girlz | Nnegest Likké | Mo'Nique | Comedy | |
| The Phobic | Margo Romero | Courtney Gains, Juliette Marquis, Eric Millegan | Thriller | |
| The Pink Panther | Shawn Levy | Steve Martin, Beyoncé Knowles, Kevin Kline, Kristin Chenoweth | Comedy | based on The Pink Panther film series |
| Pirates of the Caribbean: Dead Man's Chest | Gore Verbinski | Johnny Depp, Orlando Bloom, Keira Knightley, Geoffrey Rush | Adventure | preceded by Pirates of the Caribbean: The Curse of the Black Pearl |
| Poseidon | Wolfgang Petersen | Josh Lucas, Kurt Russell, Richard Dreyfuss, Kevin Dillon, Freddy Rodríguez, Emmy Rossum, Mike Vogel, Jacinda Barrett, Andre Braugher | Disaster film | based on The Poseidon Adventure by Paul Gallico |
| Poultrygeist: Night of the Chicken Dead | Lloyd Kaufman | Jason Yachanin | Horror comedy | based on Poltergeist and Night of the Living Dead |
| The Power of Community: How Cuba Survived Peak Oil | Faith Morgan | the economic collapse and recovery of Cuba following the fall of the Soviet Union in 1991 | Documentary | |
| Premium | Pete Chatmon | Dorian Missick, Zoe Saldana, Hill Harper | Comedy | |
| The Prisoner or: How I Planned to Kill Tony Blair | Michael Tucker, Petra Epperlein | the detainment and accusation of Yunis Khatayer Abbas | Documentary | |
| A Prairie Home Companion | Robert Altman | Garrison Keillor, Woody Harrelson, Tommy Lee Jones, Kevin Kline, Lindsay Lohan, Meryl Streep | Musical comedy | based on A Prairie Home Companion |
| The Prestige | Christopher Nolan | Hugh Jackman, Christian Bale, Scarlett Johansson, Michael Caine, Rebecca Hall, David Bowie | Crime drama | based on The Prestige by Christopher Priest |
| Puff, Puff, Pass | Mekhi Phifer | Danny Masterson, Ronnie Warner, Mekhi Phifer | Comedy | |
| Pulse | Jim Sonzero | Kristen Bell, Ian Somerhalder, Christina Milian, Rick Gonzalez | Horror | based on Kairo |
| The Pursuit of Happyness | Gabriele Muccino | Will Smith, Jaden Smith | Biography | |
| The Quick and the Undead | Gerald Nott | Clint Glenn | Horror, western | |
| Quick Pick | Will Vazquez | John Bryant | Comedy | |
| Quinceañera | Richard Glatzer, Wash Westmoreland | Emily Rios, Jesse Garcia, David W. Ross | Drama | winner of Grand Jury Prize: Dramatic |
| The Rape of the Sabine Women | Eve Sussman | Nina Adamopoulou | Drama | |
| Relative Strangers | Greg Glienna | Ron Livingston, Danny DeVito, Neve Campbell | Comedy | |
| The Return | Asif Kapadia | Sarah Michelle Gellar, Peter O'Brien, Adam Scott | Thriller | |
| Right at Your Door | Chris Gorak | Mary McCormack, Rory Cochrane | Drama | |
| Robotech: The Shadow Chronicles | Dong-Wook Lee, Tommy Yune | Richard Epcar, Eddie Frierson, Mark Hamill | Animation | preceded by Robotech |
| Rocky Balboa | Sylvester Stallone | Sylvester Stallone, Burt Young, Geraldine Hughes, Milo Ventimiglia, Antonio Tarver, Tony Burton | Drama | preceded by Rocky V |
| Roman | Angela Bettis | Lucky McKee, Kristen Bell | Drama | based on May |
| Romeo & Juliet: Sealed with a Kiss | Phil Nibbelink | Daniel Trippett, Patricia Trippett | Animation | based on Romeo and Juliet by William Shakespeare |
| Room 6 | Michael Hurst | Christine Taylor, Jerry O'Connell, Shane Brolly | Horror | |
| Rune | Seth Kenlon, Arayna Thomas | Anna Bäumer, Bill Wise | Drama | |
| Running Scared | Wayne Kramer | Paul Walker | Crime drama | |
| Running with Scissors | Ryan Murphy | Annette Bening, Brian Cox, Joseph Fiennes | Comedy-drama | based on Running with Scissors by Augusten Burroughs |
| RV | Barry Sonnenfeld | Robin Williams, Jeff Daniels, Cheryl Hines, Kristin Chenoweth, JoJo, Josh Hutcherson | Adventure | |
| ...So Goes the Nation | Adam Del Deo, James D. Stern | the 2004 Presidential Election of the United States | Documentary | |
| Sacco and Vanzetti | Peter Miller | trial of Nicola Sacco and Bartolomeo Vanzetti | Documentary | |
| The Santa Clause 3: The Escape Clause | Michael Lembeck | Tim Allen, Martin Short | Fantasy | preceded by The Santa Clause 2 |
| The Sasquatch Gang | Tim Skousen | Jeremy Sumpter, Justin Long, Joey Kern | Comedy | |
| Saving Shiloh | Sandy Tung | Scott Wilson, Gerald McRaney | Family | based on Saving Shiloh by Phyllis Reynolds Naylor
preceded by Shiloh |
| Saw III | Darren Lynn Bousman | Tobin Bell, Shawnee Smith, Angus Macfadyen, Bahar Soomekh | Horror | preceded by Saw II |
| A Scanner Darkly | Richard Linklater | Keanu Reeves, Robert Downey, Jr., Woody Harrelson, Winona Ryder | Animation | based on A Scanner Darkly by Philip K. Dick |
| Scary Movie 4 | David Zucker | Anna Faris, Regina Hall, Craig Bierko, Bill Pullman | Comedy, parody | preceded by Scary Movie 3 |
| School for Scoundrels | Todd Phillips | Billy Bob Thornton, Jon Heder | Comedy | based on School for Scoundrels |
| Scoop | Woody Allen | Scarlett Johansson, Hugh Jackman, Woody Allen, Ian McShane | Romantic comedy | |
| Scott Walker: 30 Century Man | Stephen Kijak | the career of Scott Walker | Documentary | |
| The Second Chance | Steve Taylor | Michael W. Smith, Jeff Obafemi Carr | Drama | |
| Secret of the Cave | Zach C. Gray | Patrick Bergin, Joseph Kelly | Adventure | based on Secret of the Cave by Arthur S. Maxwell |
| See No Evil | Gregory Dark | Glenn Jacobs, Christina Vidal, Samantha Noble | Horror | |
| The Sentinel | Clark Johnson | Michael Douglas, Kiefer Sutherland, Eva Longoria, Kim Basinger | Crime drama | based on The Sentinel by Gerald Petievich |
| The Shaggy Dog | Brian Robbins | Tim Allen, Kristin Davis, Spencer Breslin, Danny Glover, Robert Downey, Jr. | Comedy | based on The Shaggy Dog |
| Shark Bait | Howard E. Baker, John Fox | Freddie Prinze, Jr. | Animation | |
| She's the Man | Andy Fickman | Amanda Bynes, Channing Tatum | Romantic comedy | based on Twelfth Night by William Shakespeare |
| Sherrybaby | Laurie Collyer | Maggie Gyllenhaal, Brad William Henke, Sam Bottoms | Drama | |
| Shortbus | John Cameron Mitchell | Sook-Yin Lee | Comedy-drama | |
| Shottas | Cess Silvera | Ky-Mani Marley, Spragga Benz | Crime drama | |
| Silent Hill | Christophe Gans | Radha Mitchell, Sean Bean, Laurie Holden, Jodelle Ferland | Horror | based on the Silent Hill series |
| Simon Says | William Dear | Crispin Glover, Margo Harshman | Horror | |
| Sleeping Dogs Lie | Bobcat Goldthwait | Melinda Page Hamilton, Bryce Johnson | Comedy | |
| Slither | James Gunn | Nathan Fillion, Elizabeth Banks, Michael Rooker | Horror comedy | |
| Small Town Gay Bar | Malcolm Ingram | gay bars in rural Southeast United States | Documentary | |
| Snakes on a Plane | David R. Ellis | Samuel L. Jackson, Julianna Margulies, Taylor Kitsch, Kenan Thompson | Thriller | |
| Snow Blind | Christopher J. Scott | history, lifestyle of snowboarding | Documentary | |
| So Much So Fast | Steven Ascher, Jeanne Jordan | the life of Stephen Heywood | Documentary | |
| Something New | Sanaa Hamri | Sanaa Lathan, Simon Baker, Mike Epps, Donald Faison | Drama | |
| Sonhos de Peixe | Kirill Mikhanovsky | José Maria Alves, Phellipe Haagensen | Drama | |
| Special | Hal Haberman, Jeremy Passmore | Michael Rapaport | Drama | |
| Stalking Santa | Greg Kiefer | Daryn Tufts, William Shatner | Mockumentary | |
| Starter for 10 | Tom Vaughan | James McAvoy, Alice Eve, Rebecca Hall | Comedy-drama | based on Starter for Ten by David Nicholls |
| Stay Alive | William Brent Bell | Jon Foster, Samaire Armstrong, Frankie Muniz, Sophia Bush, Jimmie Simpson | Horror | |
| Step Up | Anne Fletcher | Channing Tatum, Jenna Dewan | Dance | |
| Stephanie Daley | Hilary Brougher | Amber Tamblyn, Tilda Swinton, Timothy Hutton | Drama | |
| Stick It | Jessica Bendinger | Jeff Bridges, Missy Peregrym | Drama | |
| Stranger Than Fiction | Marc Forster | Will Ferrell, Emma Thompson | Fantasy | |
| Stormbreaker | Peyton Horowitz | Alex Pettyfer, Ewan McGregor | Spy | Stormbreaker by Anthony Horowitz |
| Strawberry Shortcake: The Sweet Dreams Movie | Karyn Hyden | Sarah Heinke | Animation | |
| Subject Two | Philip Chidel | Christian Oliver, Dean Stapleton | Drama | |
| Suicide Killers | Pierre Rehov | the motivations of a suicide bomber | Documentary | |
| Superman Returns | Bryan Singer | Brandon Routh, Kate Bosworth, Kevin Spacey, Frank Langella, James Marsden, Eva Marie Saint | Superhero | preceded by Superman IV: The Quest for Peace |
| Swarm of the Snakehead | Frank A. Lama, Joel C. Denning | Gunnar Hansen, Frank A. Lama, Jamie O'Brien | Horror | |
| Sweet Insanity | Daniel Hess | Rebekah Isaacs, Mackenzie Firgens | Horror | |
| Take the Lead | Liz Friedlander | Antonio Banderas | Drama, dance | |
| Talladega Nights: The Ballad of Ricky Bobby | Adam McKay | Will Ferrell, John C. Reilly, Sacha Baron Cohen | Comedy | |
| The Teddy Bear Master | Charlie Ours | Isaac Imel | Horror | Produced for limited distribution by Indiana high school students and led to two separate lawsuite due to its content. |
| Tenacious D in The Pick of Destiny | Liam Lynch | Jack Black, Kyle Gass | Comedy | |
| The Texas Chainsaw Massacre: The Beginning | Jonathan Liebesman | Jordana Brewster, Taylor Handley | Horror | preceded by The Texas Chainsaw Massacre |
| Thank You for Smoking | Jason Reitman | Aaron Eckhart, Cameron Bright, Maria Bello, David Koechner | Comedy | based on Thank You for Smoking by Christopher Buckley |
| This Film Is Not Yet Rated | Kirby Dick | Motion Picture Association of America rating system | Documentary | |
| Threat | Matt Pizzolo | Carlos Puga, Katie Nisa | Drama | |
| Tomorrow Is Today | Frederic Lumiere | Scout Taylor-Compton | Drama | |
| Trantasia | Jeremy Stanford | first "World's Most Beautiful Transsexual Pageant" | Documentary | |
| Tristan & Isolde | Kevin Reynolds | James Franco, Sophia Myles, Rufus Sewell | Drama | based on Tristan und Isolde by Richard Wagner |
| Trust the Man | Bart Freundlich | Billy Crudup, David Duchovny, Maggie Gyllenhaal | Romantic comedy | |
| Turistas | John Stockwell | Josh Duhamel, Melissa George, Olivia Wilde | Horror | |
| Two Weeks | Steve Stockman | Sally Field, Ben Chaplin | Comedy-drama | |
| The U.S. vs. John Lennon | David Leaf, John Scheinfeld II | the transformation of John Lennon from a member of The Beatles to an anti-war activist | Documentary | |
| Ultraviolet | Kurt Wimmer | Milla Jovovich, Cameron Bright, Nick Chinlund, William Fichtner | Science fiction | |
| Unaccompanied Minors | Paul Feig | Lewis Black, Wilmer Valderrama, Tyler James Williams | Comedy | |
| Underworld: Evolution | Len Wiseman | Kate Beckinsale, Scott Speedman, Tony Curran | Horror | preceded by Underworld |
| Undoing | Chris Chan Lee | Sung Kang, Tom Bower, Russell Wong | Crime drama | |
| Unidentified | Rich Christiano | Jonathan Aube | Science fiction | |
| United 93 | Paul Greengrass | see Cast | Drama | |
| Unrest | Jason Todd Ipson | Corri English | Horror | |
| V for Vendetta | James McTeigue | Natalie Portman, Hugo Weaving, Stephen Rea, John Hurt | Thriller | based on V for Vendetta by Alan Moore |
| Vacationland | Todd Verow | Brad Hallowell, Gregory J. Lucas | Drama | |
| Vanaja | Rajnesh Domalpalli | Mamatha Bhukya | Drama | |
| Waist Deep | Vondie Curtis-Hall | Tyrese Gibson, Meagan Good, Larenz Tate, The Game | Crime drama | based on Bonnie and Clyde |
| The War Tapes | Deborah Scranton | the 2003 invasion of Iraq in the prospective of the soldiers | Documentary | |
| We Are Marshall | McG | Matthew McConaughey, Matthew Fox, Anthony Mackie | Drama | |
| When a Stranger Calls | Simon West | Camilla Belle | Horror | based on When a Stranger Calls |
| When I Came Home | Dan Lohaus | the homeless veterans in the United States | Documentary | |
| Who Killed the Electric Car? | Chris Paine | the creation, commercialization, and destruction of the battery electric vehicle | Documentary | |
| Wicked Little Things | J. S. Cardone | Lori Heuring, Scout Taylor-Compton, Chloë Grace Moretz | Horror | |
| The Wicker Man | Neil LaBute | Nicolas Cage, Ellen Burstyn, Kate Beahan, Frances Conroy, Leelee Sobieski, Molly Parker, Diane Delano | Horror | based on The Wicker Man |
| The Wild | Steve "Spaz" Williams | Kiefer Sutherland, James Belushi | Animation | |
| The Woods | Lucky McKee | Agnes Bruckner, Patricia Clarkson | Horror | |
| Wordplay | Patrick Creadon | Will Shortz, Bill Clinton, Jon Stewart | Documentary | crossword puzzles |
| World Trade Center | Oliver Stone | Nicolas Cage, Michael Peña, Maggie Gyllenhaal, Maria Bello | Drama | |
| Wristcutters: A Love Story | Goran Dukić | Patrick Fugit, Shannyn Sossamon, Tom Waits | Drama | |
| X-Men: The Last Stand | Brett Ratner | Hugh Jackman, Halle Berry, Patrick Stewart, Ian McKellen, Famke Janssen, James Marsden, Anna Paquin, Kelsey Grammer | Superhero | preceded by X2 |
| Yellow | Alfredo De Villa | Roselyn Sánchez, Bill Duke, D. B. Sweeney | Drama | |
| Yeti: A Love Story | Adam Deyoe, Eric Gosselin | Adam Malamut, Eric Gosselin, Laura Glascott, Loren Mash, Dave Paige | Romance-horror | |
| You, Me and Dupree | Joe Russo, Anthony Russo | Owen Wilson, Kate Hudson, Matt Dillon, Michael Douglas | Comedy | |
| Zoom | Peter Hewitt | Tim Allen, Courteney Cox | Superhero | based on Amazing Adventures from Zoom's Academy by Jason Lethcoe |
| Zyzzyx Road | John Penney | Leo Grillo, Katherine Heigl, Tom Sizemore | Thriller | |
