Mucrolysin

Mucrolysin
Identifiers
EC number 3.4.24.54
CAS number 85898-38-0
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Mucrolysin (EC 3.4.24.54, Trimeresurus metalloendopeptidase A, mucrotoxin A) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Cleavage of Ser9-His, His10-Leu, Ala14-Leu, Leu15-Tyr and Tyr16-Leu bonds in insulin B chain

This endopeptidase from the venom of Chinese habu snake (Trimeresurus mucrosquamatus).

References

  1. Sugihara, H., Moriura, M. and Nikai, T. (1983). "P'urification and properties of a lethal, hemorrhagic protein, "mucrotoxin A", from the venom of the Chinese habu snake (Trimeresurus mucrosquamatus)". Toxicon 21: 247–255. doi:10.1016/0041-0101(83)90009-0. PMID 6857709.
  2. Kishida, M., Nikai, T., Mori, N., Kohmura, S. and Sugihara, H. (1985). "Characterization of mucrotoxin A from the venom of Trimeresurus mucrosquamatus (the Chinese habu snake)". Toxicon 23: 637–645. doi:10.1016/0041-0101(85)90368-x. PMID 3904081.

External links

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