Cinchocaine

Cinchocaine
Systematic (IUPAC) name
2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide
Clinical data
AHFS/Drugs.com International Drug Names
Routes of
administration
topical, intravenous (equine euthanasia)
Legal status
Legal status
Identifiers
CAS Number 85-79-0 YesY
ATC code C05AD04 (WHO) D04AB02 N01BB06 S01HA06 S02DA04
PubChem CID 3025
IUPHAR/BPS 7159
DrugBank DB00527 YesY
ChemSpider 2917 YesY
UNII L6JW2TJG99 YesY
KEGG D00733 YesY
ChEBI CHEBI:247956 YesY
ChEMBL CHEMBL1086 YesY
Chemical data
Formula C20H29N3O2
Molar mass 343.463 g/mol
  (verify)

Cinchocaine (INN/BAN) or dibucaine (USAN) is an amide local anesthetic. Among the most potent and toxic of the long-acting local anesthetics, current use of cinchocaine is generally restricted to spinal and topical anesthesia.[1][2] It is sold under the brand names Cincain, Nupercainal, Nupercaine and Sovcaine.

Medical use

Cinchocaine is the active ingredient in some topical hemorrhoid creams such as Proctosedyl. It is also a component of the veterinary drug Somulose, used for euthanasia of horses and cattle.

Physical properties

Cinchocaine is relatively insoluble in alkaline aqueous solutions.

See also

References

  1. Martindale, The Extra Pharmacopoeia, 30th ed, p1006
  2. Dibucaine

Further reading

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