Renal compensation

Renal compensation is a mechanism by which the kidneys can regulate the plasma pH. It is slower than respiratory compensation, but has a greater ability to restore normal values.

In respiratory acidosis, the kidney produces and excretes ammonium (NH₄⁺) and monophosphate, generating bicarbonate in the process while clearing acid.^[1]

In respiratory alkalosis, less HCO₃⁻ is reabsorbed, thus lowering the pH.^[2]

References

↑ Physiology: 7/7ch12/7ch12p45 - Essentials of Human Physiology
↑ Physiology: 7/7ch12/7ch12p48 - Essentials of Human Physiology

External links

Physiology of the kidneys and acid-base physiology

Renal function

Secretion	clearance Pharmacokinetics Clearance of medications Urine flow rate

Reabsorption	Solvent drag sodium chloride urea glucose oligopeptides protein

Renal function	Glomerular filtration rate Creatinine clearance Renal clearance ratio Urea reduction ratio Kt/V Standardized Kt/V Measures of dialysis Hemodialysis product PAH clearance (Effective renal plasma flow Extraction ratio)

Filtration	Renal blood flow Ultrafiltration Countercurrent exchange Filtration fraction

Hormones

Acid-base balance

Body water: Intracellular fluid/Cytosol

Buffering

Other

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