Solvent drag

Solvent drag, also known as bulk transport, refers to solutes in the ultrafiltrate that are transported back from the renal tubule by the flow of water rather than specifically by ion pumps or other membrane transport proteins.^[1] This is a phenomenon primarily in renal physiology, but it also occurs in gastrointestinal physiology.

It generally occurs in the paracellular, rather than transcellular, pathway across the tubular cells.

It is seen e.g. in the passive transport in renal sodium reabsorption, renal chloride reabsorption as well as renal urea handling.

References

↑ Walter F., PhD. Boron. Medical Physiology: A Cellular And Molecular Approach. Elsevier/Saunders. ISBN 1-4160-2328-3. Page 791

Physiology of the kidneys and acid-base physiology

Renal function

Secretion	clearance Pharmacokinetics Clearance of medications Urine flow rate

Reabsorption	Solvent drag sodium chloride urea glucose oligopeptides protein

Renal function	Glomerular filtration rate Creatinine clearance Renal clearance ratio Urea reduction ratio Kt/V Standardized Kt/V Measures of dialysis Hemodialysis product PAH clearance (Effective renal plasma flow Extraction ratio)

Filtration	Renal blood flow Ultrafiltration Countercurrent exchange Filtration fraction

Hormones

Acid-base balance

Body water: Intracellular fluid/Cytosol

Buffering

Other

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