Sortase B

Sortase B
Identifiers
EC number	3.4.22.71
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Sortase B (EC 3.4.22.71, SrtB) is an enzyme.^[1][2] This enzyme catalyses the following chemical reaction

The enzyme catalyses a cell wall sorting reaction in which a surface protein with a sorting signal containing a NXTN motif is cleaved.

This enzyme belongs to the peptidase family C60.

References

1. Zong, Y., Mazmanian, S.K., Schneewind, O. and Narayana, S.V. (2004). "The structure of sortase B, a cysteine transpeptidase that tethers surface protein to the Staphylococcus aureus cell wall". Structure 12: 105–112. doi:10.1016/j.str.2003.11.021. PMID 14725770.
2. Bierne, H., Garandeau, C., Pucciarelli, M.G., Sabet, C., Newton, S., Garcia-del Portillo, F., Cossart, P. and Charbit, A. (2004). "Sortase B, a new class of sortase in Listeria monocytogenes". J. Bacteriol. 186: 1972–1982. doi:10.1128/jb.186.7.1972-1982.2004. PMID 15028680.

External links

• Sortase B at the US National Library of Medicine Medical Subject Headings (MeSH)