Syn-copalyl-diphosphate synthase

Syn-copalyl-diphosphate synthase (EC 5.5.1.14, OsCyc1, OsCPSsyn, syn-CPP synthase, syn-copalyl diphosphate synthase) is an enzyme with systematic name 9alpha-copalyl-diphosphate lyase (decyclizing).^[1]^[2] This enzyme catalyses the following chemical reaction

geranylgeranyl diphosphate

\rightleftharpoons

9alpha-copalyl diphosphate

This enzyme requires a divalent metal ion, preferably Mg²⁺, for activity.

References

↑ Otomo, K., Kenmoku, H., Oikawa, H., Konig, W.A., Toshima, H., Mitsuhashi, W., Yamane, H., Sassa, T. and Toyomasu, T. (2004). "Biological functions of ent- and syn-copalyl diphosphate synthases in rice: key enzymes for the branch point of gibberellin and phytoalexin biosynthesis". Plant J. 39 (6): 886–893. doi:10.1111/j.1365-313X.2004.02175.x. PMID 15341631.
↑ Xu, M., Hillwig, M.L., Prisic, S., Coates, R.M. and Peters, R.J. (2004). "Functional identification of rice syn-copalyl diphosphate synthase and its role in initiating biosynthesis of diterpenoid phytoalexin/allelopathic natural products". Plant J. 39 (3): 309–318. doi:10.1111/j.1365-313X.2004.02137.x. PMID 15255861.

External links

Syn-copalyl-diphosphate synthase at the US National Library of Medicine Medical Subject Headings (MeSH)

Isomerase: Intramolecular Lyases (EC 5.5)

5.5.1 Intramolecular Lyases

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases(list) EC2 Transferases(list) EC3 Hydrolases(list) EC4 Lyases(list) EC5 Isomerases(list) EC6 Ligases(list)

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