TMX1

Thioredoxin-related transmembrane protein 1
PDB rendering based on 1x5e.
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 1X5E​
Identifiers
Symbols	TMX1 ; PDIA11; TMX; TXNDC; TXNDC1
External IDs	OMIM: 610527 MGI: 1919986 HomoloGene: 12482 GeneCards: TMX1 Gene
Gene ontology Molecular function • protein disulfide isomerase activity • disulfide oxidoreductase activity Cellular component • nucleolus • endoplasmic reticulum • endoplasmic reticulum membrane • integral component of membrane Biological process • protein folding • response to endoplasmic reticulum stress • cell redox homeostasis • oxidation-reduction process Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	81542	72736
Ensembl	ENSG00000139921	ENSMUSG00000021072
UniProt	Q9H3N1	Q8VBT0
RefSeq (mRNA)	NM_030755	NM_028339
RefSeq (protein)	NP_110382	NP_082615
Location (UCSC)	Chr 14: 51.24 – 51.26 Mb	Chr 12: 70.45 – 70.47 Mb
PubMed search

Thioredoxin-related transmembrane protein 1 is a protein that in humans is encoded by the TMX1 gene.^[1][2]

References

1. Matsuo Y, Akiyama N, Nakamura H, Yodoi J, Noda M, Kizaka-Kondoh S (Mar 2001). "Identification of a novel thioredoxin-related transmembrane protein". J Biol Chem 276 (13): 10032–8. doi:10.1074/jbc.M011037200. PMID 11152479.
2. "Entrez Gene: TXNDC1 thioredoxin domain containing 1".

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Heilig R, Eckenberg R, Petit JL, et al. (2003). "The DNA sequence and analysis of human chromosome 14.". Nature 421 (6923): 601–7. doi:10.1038/nature01348. PMID 12508121.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.