Tenoten

Tenoten
Clinical data
Trade names Тенотен
Legal status
Legal status
  • US: Unscheduled
  • OTC (RU)
Identifiers
ATC code None

Tenoten (Russian: Тенотен) is the trade name of a homeopathic preparation that is marketed in Russia as an anxiolytic by Materia Medica Holding Scientific and Production Company.[1][2] It is said to also possess antidepressant and nootropic properties,[3][4][5] and has been reported to be effective in the treatment of chronic tension headaches in children.[6] Tenoten is described as acting as an antibody of the brain-specific protein S-100B.[4]

Other antibodies of S-100 that are approved for clinical use in Russia include Proproten (or Proproten-100) (Russian: Пропротен-100), Brizantin (Russian: Бризантин) and Divaza (Russian: Диваза).[7][8] They all similarly have been reported to possess anxiolytic and antidepressant properties.[9][10][11]

See also

References

  1. ↑ Под ред. Т.Б. Дмитриевой, В.Н. Краснова, Н.Г. Незнанова, В.Я. Семке, А.С. Тиганова. Психиатрия: нац. рук. ГЭОТАР-Медиа. pp. 971–. ISBN 978-5-9704-2030-0.
  2. ↑ Larentsova LI, Lyubimova DV, Fokina TY, Rvacheva EA, Sosul'nikov DV (2009). "The use of tenoten and tenoten (pediatric formulation) as a drug for premedication in adults and children during outpatients dentist visit". Bull. Exp. Biol. Med. 148 (2): 340–2. PMID 20027365.
  3. ↑ Delger AB, Avakyan GN, Oleinikova OM, Bogomazova MA, Chromych EA, Lagutin IuV (2012). "Effects of tenoten on anxiety and depression disorders in patients with epilepsy". Bull. Exp. Biol. Med. 153 (5): 704–6. PMID 23113263.
  4. 1 2 Duma SA, Shishkin SV (2009). "Tenoten in the therapy of patients with moderate cognitive impairment". Bull. Exp. Biol. Med. 148 (2): 353–6. PMID 20027370.
  5. ↑ Voronina TA, Molodavkin GM, Borodavkina MV, Kheyfets IA, Dugina YL, Sergeeva SA (2009). "Nootropic and antiamnestic effects of tenoten (pediatric formulation) in immature rat pups". Bull. Exp. Biol. Med. 148 (3): 524–6. PMID 20396730.
  6. ↑ Barkhatov MV, Barkhatova SY, Nosyrev AV, Zorin NA, Borodavkina MV, Kheifets IA, Kachanova MV, Sabanov LV (2009). "The use of tenoten (pediatric formulation) in the therapy of chronic tension-type headaches in children". Bull. Exp. Biol. Med. 148 (2): 337–9. PMID 20027364.
  7. ↑ Gofman AG, Pyatnitskaya IN, Valentik YV, Krylov EN, Epstein OI (2003). "Proproten-100 in the therapy of patients with the alcohol withdrawal syndrome". Bull. Exp. Biol. Med. 135 Suppl 7: 167–70. PMID 12949689.
  8. ↑ Barchukov, V. V.; Zhavbert, E. S.; Dugina, Yu. L.; Epstein, O. I. (2015). "The Use of Release-Active Antibody-Based Preparations for Vertigo Prevention in Adults". Bulletin of Experimental Biology and Medicine 160 (1): 61–63. doi:10.1007/s10517-015-3098-z. ISSN 0007-4888.
  9. ↑ Epstein OI, Molodavkin GM, Voronina TA, Sergeeva SA (2003). "Antidepressant properties of Proproten and amitriptyline: comparative experimental study". Bull. Exp. Biol. Med. 135 Suppl 7: 123–4. PMID 12949674.
  10. ↑ Voronina TA, Epshteĭn OI, Molodavkin GM, Sergeeva SA, Kraĭneva VA (2003). "[Spectrum of psychotropic effects and mechanism of action of ultra low doses of the antibodies to S-100 protein (proproten)]". Radiats Biol Radioecol (in Russian) 43 (3): 291–3. PMID 12881981.
  11. ↑ Yakovleva, N. N.; Voronina, T. A.; Suslov, N. I.; Ertuzun, I. A.; Molodavkin, G. M.; Poseva, V. I.; Andreeva, V. V.; Dugina, Yu. L.; Putilovskii, M. A.; Epshtein, O. I. (2015). "Anxiolytic and Antidepressant Effects of Divaza and Brizantin". Bulletin of Experimental Biology and Medicine 159 (6): 753–756. doi:10.1007/s10517-015-3067-6. ISSN 0007-4888.

External links

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