Tetrahymanol synthase
Tetrahymanol synthase (EC 4.2.1.123, squaleneatetrahymanol cyclase) is an enzyme with systematic name squalene hydro-lyase (tetrahymanol forming).[1][2] This enzyme catalyses the following chemical reaction
- tetrahymanol squalene + H2O
The reaction occurs in the reverse direction.
References
- ↑ Saar, J., Kader, J.C., Poralla, K. and Ourisson, G. (1991). "Purification and some properties of the squalene-tetrahymanol cyclase from Tetrahymena thermophila". Biochim. Biophys. Acta 1075: 93–101. doi:10.1016/0304-4165(91)90080-z. PMID 1892870.
- ↑ Giner, J.L., Rocchetti, S., Neunlist, S., Rohmer, M. and Arigoni, D. (2005). "Detection of 1,2-hydride shifts in the formation of euph-7-ene by the squalene-tetrahymanol cyclase of Tetrahymena pyriformis". Chem. Commun. (Camb.): 3089–3091. doi:10.1039/b504300j. PMID 15959594.
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