20-Dihydroprogesterone

20α-Dihydroprogesterone

Identifiers
CAS Number	145-14-2^[yes]
ChemSpider	83725
EC Number	205-649-5
Jmol interactive 3D	Image
MeSH	20-alpha-Dihydroprogesterone
PubChem	8956
InChI InChI=1/C21H32O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12-13,16-19,22H,4-11H2,1-3H3/t13-,16+,17-,18+,19+,20+,21-/m1/s1 Key: RWBRUCCWZPSBFC-SJOKZOANBK
SMILES O=C4\C=C2/[C@]([C@H]1CC[C@@]3([C@H](CC[C@H]3[C@@H]1CC2)[C@H](O)C)C)(C)CC4
Properties
Chemical formula	C21H32O2
Molar mass	316.478 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

20α-Dihydroprogesterone, or 20α-hydroxyprogesterone, is a naturally-occurring, endogenous progestogen.^[1][2][3] It is a metabolite of progesterone, converted by the 20α-hydroxysteroid dehydrogenases AKR1C1 and AKR1C3, and although still active as a progestogen,^[4] is much less potent in comparison.^[1][2][3]

See also

• 17α-Hydroxyprogesterone
• 5α-Dihydroprogesterone

References

1. Beranič N, Gobec S, Rižner TL (2011). "Progestins as inhibitors of the human 20-ketosteroid reductases, AKR1C1 and AKR1C3". Chem. Biol. Interact. 191 (1-3): 227–33. doi:10.1016/j.cbi.2010.12.012. PMID 21182831.
2. Tony M. Plant; Anthony J. Zeleznik (15 November 2014). Knobil and Neill's Physiology of Reproduction: Two-Volume Set. Academic Press. pp. 1–. ISBN 978-0-12-397769-4.
3. Cynthia L. Darlington (27 April 2009). The Female Brain. CRC Press. pp. 4–. ISBN 978-1-4200-7745-2.
4. Marianne J. Legato (29 October 2009). Principles of Gender-Specific Medicine. Academic Press. pp. 617–. ISBN 978-0-08-092150-1.