A-1,4-glucan-protein synthase (UDP-forming)

Alpha-1,4-glucan-protein synthase (UDP-forming)
Identifiers
EC number 2.4.1.112
CAS number 152478-54-1
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Alpha-1,4-glucan-protein synthase (UDP-forming) (EC 2.4.1.112, UDP-glucose:protein glucosyltransferase, glycogen initiator synthase, UDPGlc:protein transglucosylase, UPTG, uridine diphosphoglucose protein transglucosylase I, proglycogen synthase, uridine diphosphoglucose-protein 4-alpha-glucosyltransferase, uridine diphosphoglucose-protein glucosyltransferase, UDP-glucose protein transglucosylase, UDP-glucose-protein glucosyltransferase, uridine diphosphate glucose-protein transglucosylase I) is an enzyme with systematic name UDP-glucose:protein 4-alpha-glucosyltransferase.[1][2][3] This enzyme catalyses the following chemical reaction

UDP-glucose + protein \rightleftharpoons UDP + alpha-D-glucosyl-protein

The enzyme builds up alpha-1,4-glucan chains covalently bound to protein.

References

  1. Barengo, R. and Krisman, C.R. (1978). "Initiation of glycogen biosynthesis in Escherichia coli. Studies of the properties of the enzymes involved". Biochim. Biophys. Acta 540 (2): 190–196. doi:10.1016/0304-4165(78)90131-9. PMID 418819.
  2. Butler, N.A., Lee, E.Y.C. and Whelan, W.J. (1977). "A protein-bound glycogen component of rat liver". Carbohydr. Res. 55: 73–82. doi:10.1016/s0008-6215(00)84444-4. PMID 861979.
  3. Krisman, C.R. and Barengo, R. (1975). "A precursor of glycogen biosynthesis: α-1,4-glucan-protein". Eur. J. Biochem. 52: 117–123. doi:10.1111/j.1432-1033.1975.tb03979.x. PMID 809265.

External links

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