Alginate synthase

alginate synthase
Identifiers
EC number	2.4.1.33
CAS number	37257-31-1
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, an alginate synthase (EC 2.4.1.33) is an enzyme that catalyzes the chemical reaction

GDP-D-mannuronate + (alginate)n $\rightleftharpoons$ GDP + (alginate)n⁺1

Thus, the two substrates of this enzyme are GDP-D-mannuronate and (alginate)n, whereas its two products are GDP and (alginate)n+1.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-D-mannuronate:alginate D-mannuronyltransferase. This enzyme is also called mannuronosyl transferase. This enzyme participates in fructose and mannose metabolism.

References

• Lin TY, Hassid WZ (1966). "Pathway of algnic acid synthesis in the marine brown alga, Fucus gardneri Silva". J. Biol. Chem. 241 (22): 5284–97. PMID 5954796.