Astromicin

Astromicin
Systematic (IUPAC) name

2-amino-N-[(1S,2R,3R,4S,5S,6R)-4-amino-3-[(2R,3R,6S)-3-amino-6-(1-aminoethyl)oxan-2-yl]oxy-2,5-dihydroxy-6-methoxycyclohexyl]-N-methylacetamide
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of administration	IV
Legal status	℞ (Prescription only)
Identifiers
CAS Number	55779-06-1^N
ATC code	none
PubChem	CID 65345
ChemSpider	4447577^Y
UNII	7JHD84H15J^Y
KEGG	D07470^Y
ChEBI	CHEBI:37923^N
ChEMBL	CHEMBL1909053^N
Chemical data
Formula	C₁₇H₃₅N₅O₆
Molar mass	405.48 g/mol
SMILES O=C(N(C)[C@@H]2[C@@H](OC)[C@@H](O)[C@H](N)[C@@H](O[C@H]1O[C@H]([C@@H](N)C)CC[C@H]1N)[C@@H]2O)CN
InChI InChI=1S/C17H35N5O6/c1-7(19)9-5-4-8(20)17(27-9)28-15-11(21)13(24)16(26-3)12(14(15)25)22(2)10(23)6-18/h7-9,11-17,24-25H,4-6,18-21H2,1-3H3/t7-,8+,9-,11-,12-,13-,14+,15+,16+,17+/m0/s1^Y Key:BIDUPMYXGFNAEJ-APGVDKLISA-N^Y
^NY (what is this?) (verify)

Astromicin (INN)(also frequently referenced in scientific journal articles as compounds Fortimicin A/B ) is an aminoglycoside antibiotic. Synthesized from Micromonospora olivasterospora(also named with additional o in olivoasterospora).

Antibacterials: protein synthesis inhibitors (J01A, J01B, J01F, J01G, QJ01XQ)

30S

Aminoglycosides
(initiation inhibitors)

-mycin (Streptomyces)	Streptomycin^# Dihydrostreptomycin Neomycin^# Framycetin Paromomycin Ribostamycin Kanamycin^# Amikacin Arbekacin Bekanamycin Dibekacin Tobramycin Spectinomycin^# Hygromycin B Paromomycin

-micin (Micromonospora)	Gentamicin^# Netilmicin Sisomicin Isepamicin Verdamicin Astromicin

Tetracycline antibiotics
(tRNA binding)

Tetracyclines	Doxycycline^# Chlortetracycline Clomocycline Demeclocycline Lymecycline Meclocycline Metacycline Minocycline Oxytetracycline Penimepicycline Rolitetracycline Tetracycline

Glycylcyclines	Tigecycline

50S

Oxazolidinone
(initiation inhibitors)

Peptidyl transferase

Amphenicols	Chloramphenicol^# Azidamfenicol Thiamphenicol Florfenicol

Pleuromutilins	Retapamulin Tiamulin Valnemulin

MLS (transpeptidation/translocation)

Macrolides	Azithromycin^# Clarithromycin Dirithromycin Erythromycin^# Flurithromycin Josamycin Midecamycin Miocamycin Oleandomycin Rokitamycin Roxithromycin Spiramycin Troleandomycin Tylosin Ketolides Telithromycin Cethromycin Solithromycin^†

Lincosamides	Clindamycin^# Lincomycin Pirlimycin

Streptogramins	Pristinamycin Quinupristin/dalfopristin Virginiamycin

EF-G

Steroid antibacterials	Fusidic acid

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

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