Eperezolid

Eperezolid

Systematic (IUPAC) name
(S)-N-[[3-[3-Fluoro-4-[4-(2-hydroxyacetyl)piperazin- 1-yl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide
Identifiers
CAS Number	165800-04-4
ATC code	none
PubChem	CID 73214
ChemSpider	65969
UNII	C460ZSU1OW
KEGG	D04017
ChEMBL	CHEMBL47955
Chemical data
Formula	C18H23FN4O5
Molar mass	394.40
SMILES CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCN(CC3)C(=O)CO)F
InChI InChI=1S/C18H23FN4O5/c1-12(25)20-9-14-10-23(18(27)28-14)13-2-3-16(15(19)8-13)21-4-6-22(7-5-21)17(26)11-24/h2-3,8,14,24H,4-7,9-11H2,1H3,(H,20,25)/t14-/m0/s1 Key:SIMWTRCFFSTNMG-AWEZNQCLSA-N
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Eperezolid is an oxazolidinone antibiotic.

Synthesis

Eperezolid synthesis ^[1]

See also

Linezolid

References

1. Brickner, S. J.; Hutchinson, D. K.; Barbachyn, M. R.; Manninen, P. R.; Ulanowicz, D. A.; Garmon, S. A.; Grega, K. C.; Hendges, S. K.; Toops, D. S.; Ford, C. W.; Zurenko, G. E. (1996). "Synthesis and Antibacterial Activity of U-100592 and U-100766, Two Oxazolidinone Antibacterial Agents for the Potential Treatment of Multidrug-Resistant Gram-Positive Bacterial Infections". Journal of Medicinal Chemistry 39 (3): 673–9. doi:10.1021/jm9509556. PMID 8576909.