Chlormerodrin

Chlormerodrin
Systematic (IUPAC) name


[3-(Carbamoylamino)-2-methoxypropyl](chloro)mercury
Clinical data
AHFS/Drugs.com	Medical Encyclopedia
Legal status
Legal status	US: Withdrawn
Identifiers
CAS Number	62-37-3
ATC code	none
PubChem	CID 25210
DrugBank	DB00534
ChemSpider	2615
ChEBI	CHEBI:59445
ChEMBL	CHEMBL2110562
Chemical data
Formula	C₅H₁₁ClHgN₂O₂
Molar mass	367.196 g/mol
SMILES COC(CNC(=O)N)C[Hg]Cl
InChI InChI=1S/C5H11N2O2.ClH.Hg/c1-4(9-2)3-7-5(6)8;;/h4H,1,3H2,2H3,(H3,6,7,8);1H;/q;;+1/p-1 Key:BJFGVYCULWBXKF-UHFFFAOYSA-M

Chlormerodrin is a mercurial diuretic that was once used to treat patients with heart failure, but is no longer used in the United States.^[1]

References

↑ MedlinePlus > Chlormerodrin overdose Update Date: 1/15/2010. Updated by: Jacob L. Heller. Also reviewed by David Zieve

Antihypertensives: diuretics (C03)

Sulfonamides
(and etacrynic acid)

CA inhibitors (at PT)	Acetazolamide

Loop (Na-K-Cl at AL)	Furosemide^# Bumetanide Etacrynic acid Etozoline Muzolimine Piretanide Tienilic acid Torasemide

Thiazides (Na-Cl at DCT, Calcium-sparing)	Altizide Bendroflumethiazide Chlorothiazide Cyclopenthiazide Cyclothiazide Epitizide Hydrochlorothiazide^# Hydroflumethiazide Mebutizide Methyclothiazide Polythiazide Trichlormethiazide

Thiazide-likes (primarily DCT)	Quinethazone Clopamide Chlortalidone Mefruside Clofenamide Metolazone Meticrane Xipamide Indapamide Clorexolone Fenquizone

Potassium-sparing (at CD)

ESC blockers	Amiloride^# Triamterene Benzamil

Aldosterone antagonists	Spirolactones: Spironolactone^# Eplerenone Potassium canrenoate Canrenone Non-steroidal: Finerenone

Osmotic diuretics (PT, DL)

Vasopressin receptor inhibitors
(DCT and CD)

Other

Ethanol, Isopropanol, 2M2B
mercurial diuretics (Chlormerodrin, Mersalyl, Meralluride)
Theobromine
Cicletanine

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

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