Complement component 7

complement component 7
Identifiers
Symbol	C7
Entrez	730
HUGO	1346
OMIM	217070
RefSeq	NM_000587
UniProt	P10643
Other data
Locus	Chr. 5 p13

Complement component 7 is a protein involved in the complement system, where its primary task is to bind the C5bC6 complex together. This junction alters the configuration of the protein molecules exposing a hydrophobic site on C7 that allows the C7 to insert into the phospholipid bilayer of the pathogen.

External links

Complement C7 at the US National Library of Medicine Medical Subject Headings (MeSH)

Proteins: complement system (C, L, A)

Activators/enzymes

Early	C: C1Q/C1R/C1S C4 C4a C4b C2 L: MASP1/MASP2 MBL A: Factor B Factor D Factor P/Properdin

Middle	C3 C3a C3b/iC3b C5 C5a C3-convertase C5-convertase

Late	MAC C6 C7 C8 C9

Inhibitors

CL: C4BP

A: Factor H

Complement receptors

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