Conjugated estrogen

Estrone sulfate, the main active agent of conjugated estrogen formulations.

Conjugated estrogens, or conjugated equine estrogens (CEEs), are blended equine estrogens,^[1] which may include estrone sulfate, equilin sulfate, and equilenin sulfate.^[1] CEEs are used clinically in hormone replacement therapy, with marketed products including both natural preparations isolated from the urine of pregnant mares (brand names Premarin) as well as fully synthetic replications of the natural preparations (brand names Cenestin, Enjuvia, Congest, and C.E.S.).^[2][3] Prempro and Premphase are combination formulations of natural CEEs with medroxyprogesterone acetate.^[4]

See also

• Esterified estrogen
• Estrogen ester
• Ethinyl estradiol
• Estradiol
• Estropipate
• Diethylstilbestrol

References

1. Marc A. Fritz; Leon Speroff (28 March 2012). Clinical Gynecologic Endocrinology and Infertility. Lippincott Williams & Wilkins. pp. 751–. ISBN 978-1-4511-4847-3.
2. Kathy Moscou; Karen Snipe (1 December 2012). Pharmacology for Pharmacy Technicians Pageburst E-Book on VitalSource2: Pharmacology for Pharmacy Technicians Pageburst E-Book on VitalSource. Elsevier Health Sciences. pp. 573–. ISBN 0-323-08578-4.
3. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans; World Health Organization; International Agency for Research on Cancer (2007). Combined Estrogen-progestogen Contraceptives and Combined Estrogen-progestogen Menopausal Therapy. World Health Organization. pp. 378–. ISBN 978-92-832-1291-1.
4. MaryAnne Hochadel; Jerry Avorn (1 January 2007). The AARP Guide to Pills: Essential Information on More Than 1,200 Prescription and Nonprescription Medications, Including Generics. Sterling Publishing Company Incorporated. pp. 235–. ISBN 978-1-4027-4446-4.