Corilagin

Corilagin
Names
IUPAC name
[3,5-dihydroxy-2-(3,4,5-trihydroxybenzoyl)oxy-6-[(3,4,5-trihydroxybenzoyl)oxymethyl]oxan-4-yl] 3,4,5-trihydroxybenzoate
Other names
beta-1-O-galloyl-3,6-(R)-hexahydroxydiphenoyl-d-glucose
Identifiers
23094-69-1 N=
ChEMBL ChEMBL449392 N
ChemSpider 4265734 N
Jmol interactive 3D Image
Image
PubChem 73568
Properties
C27H22O18
Molar mass 634.45 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Corilagin is an ellagitannin. Corilagin was first isolated in 1951 from Dividivi extract and from Caesalpinia coriaria,[1][2] hence the name of the molecule. It can also be found in Alchornea glandulosa and in the leaves of Punica granatum (pomegranate).[3]

It is a weak carbonic anhydrase inhibitor.[4]

References

  1. Schmidt, O. T. .; Lademann, R. (1951). "Corilagin, ein weiterer kristallisierter Gerbstoff aus Dividivi. X. Mitteilung über natürliche Gerbstoffe". Justus Liebigs Annalen der Chemie 571 (3): 232. doi:10.1002/jlac.19515710305.
  2. Schmidt, O. T.; Schmidt, D. M. (1952). "Die Umwandlung von Chebulagsäure in Corilagin XIV. Mitteilung über natürliche Gerbstoffe". Justus Liebigs Annalen der Chemie 578: 25. doi:10.1002/jlac.19525780105.
  3. Tanaka, T.; Nonaka, G. I.; Nishioka, I. (1985). "Punicafolin, an ellagitannin from the leaves of Punica granatum". Phytochemistry 24 (9): 2075. doi:10.1016/S0031-9422(00)83125-8.
  4. Satomi, H.; Umemura, K.; Ueno, A.; Hatano, T.; Okuda, T.; Noro, T. (1993). "Carbonic anhydrase inhibitors from the pericarps of Punica granatum L". Biological & Pharmaceutical Bulletin 16 (8): 787–790. doi:10.1248/bpb.16.787. PMID 8220326.


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