Deoxyribonuclease IV

Deoxyribonuclease IV (phage-T4-induced)
Identifiers
EC number 3.1.21.2
CAS number 63363-78-0
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Deoxyribonuclease IV (phage-T4-induced) (EC 3.1.21.2, endodeoxyribonuclease IV (phage T4-induced), E. coli endonuclease IV, endodeoxyribonuclease, redoxyendonuclease, deoxriboendonuclease, Escherichia coli endonuclease II, endonuclease II, DNA-adenine-transferase) is an enzyme.[1][2][3][4] This enzyme catalyses the following chemical reaction

Endonucleolytic cleavage to 5'-phosphooligonucleotide end-products

Deoxyribonuclease IV is a type of deoxyribonuclease that functions at AP-sites.

References

  1. ↑ Friedberg, E.C. and Goldthwait, D.A. (1969). "Endonuclease II of E. coli. I. Isolation and purification". Proc. Natl. Acad. Sci. USA 62 (3): 934–940. doi:10.1073/pnas.62.3.934. PMC 223688. PMID 4895219.
  2. ↑ Friedberg, E.C., Hadi, S.-M. and Goldthwait, D.A. (1969). "Endonuclease II of Escherichia coli. II. Enzyme properties and studies on the degradation of alkylated and native deoxyribonucleic acid". J. Biol. Chem. 244 (21): 5879–5889. PMID 4981786.
  3. ↑ Hadi, S.M. and Goldthwait, D.A. (1971). "Endonuclease II of Escherichia coli. Degradation of partially depurinated deoxyribonucleic acid". Biochemistry 10 (26): 4986–4993. doi:10.1021/bi00802a024. PMID 4944066.
  4. ↑ Sadowski, P.D. and Hurwitz, J. (1969). "Enzymatic breakage of deoxyribonucleic acid. I. Purification and properties of endonuclease II from T4 phage-infected Escherichia coli". J. Biol. Chem. 244 (22): 6182–6191. PMID 4310836.

See also

External links

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