Evoxine

Evoxine
Names
IUPAC name
(±)-1-(4,8-Dimethoxyfuro[2,3-b]quinolin-7-yl)oxy-3-methylbutane-2,3-diol
Other names
Haploperine
Identifiers
522-11-2
ChEMBL ChEMBL1416006
ChemSpider 66130
Jmol interactive 3D Image
PubChem 73416
Properties
C18H21NO6
Molar mass 347.37 g·mol−1
Pharmacology
ATC code None
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Evoxine (haploperine) is a furoquinoline alkaloid with hypnotic and sedative effects. It is found naturally in a variety of Australian and African plants including Evodia xanthoxyloides[1] and Teclea gerrardii.[2]

References

  1. Eastwood, FW; Hughes, GK; Ritchie, E. (1954). "Alkaloids of the Australian Rutaceae: Evodia xanthoxyloides F.Muell. IV. The structures of Evoxine and Evoxoidine". Australian Journal of Chemistry 7 (1): 87–98. doi:10.1071/CH9540087.
  2. Waffo, AF; Coombes, PH; Crouch, NR; Mulholland, DA; El Amin, SM; Smith, PJ (2007). "Acridone and furoquinoline alkaloids from Teclea gerrardii (Rutaceae: Toddalioideae) of southern Africa.". Phytochemistry 68 (5): 663–7. doi:10.1016/j.phytochem.2006.10.011. PMID 17174364.


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