Proxibarbital

Proxibarbital
Systematic (IUPAC) name
(RS)-5-allyl-5-(2-hydroxypropyl)pyrimidine-2,4,6(1H,3H,5H)-trione
Identifiers
CAS Number 2537-29-3 N
ATC code N05CA22 (WHO)
PubChem CID 17336
ChemSpider 16406 YesY
Synonyms Proxibarbital, Centralgol, Ipronal, 5-Allyl-5-(β-hydroxypropyl)barbituric acid
Chemical data
Formula C10H14N2O4
Molar mass 226.229 g/mol
 NYesY (what is this?)  (verify)

Proxibarbital (Ipronal) is a barbiturate derivative synthesized in 1956. It has anti-anxiety properties and in contrast to most barbiturates almost without hypnotic action.[1]

It was also used in the treatment of migraine headaches in a similar manner to butalbital.[2]

References

  1. Zajdel, P.; Kulig, K.; Zejc, A. (2008). Zejc, A.; Gorczyca, M., eds. Chemia leków, podręcznik dla studentów farmacji i farmaceutów (in Polish). Warszawa, Poland. ISBN 978-83-200-3652-7.
  2. Sulman, F. G.; Pfeifer, Y.; Tal, E. (1976). "Migraine therapy by enzyme induction with proxibarbital". Therapie der Gegenwart (in German) 115 (12): 2088–2103. PMID 14412.



This article is issued from Wikipedia - version of the Saturday, April 02, 2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.