Flavanone 7-O-beta-glucosyltransferase

flavanone 7-O-beta-glucosyltransferase
Identifiers
EC number	2.4.1.185
CAS number	125752-73-0
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a flavanone 7-O-beta-glucosyltransferase (EC 2.4.1.185) is an enzyme that catalyzes the chemical reaction

UDP-glucose + a flavanone $\rightleftharpoons$ UDP + a flavanone 7-O-beta-D-glucoside

Thus, the two substrates of this enzyme are UDP-glucose and flavanone, whereas its two products are UDP and flavanone 7-O-beta-D-glucoside.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:flavanone 7-O-beta-D-glucosyltransferase. Other names in common use include uridine diphosphoglucose-flavanone 7-O-glucosyltransferase, naringenin 7-O-glucosyltransferase, and hesperetin 7-O-glucosyl-transferase.

References

• McIntosh CA, Latchinian L, Mansell RL (1990). "Flavanone-specific 7-O-glucosyltransferase activity in Citrus paradisi seedlings: purification and characterization". Arch. Biochem. Biophys. 282 (1): 50–7. doi:10.1016/0003-9861(90)90085-D. PMID 2171434.
• McIntosh CA and Mansell RL (1990). "Biosynthesis of naringin in Citrus paradisi - UDP-glucosyl-transferase activity in grapefruit seedlings". Phytochemistry 29 (5): 1533–1538. doi:10.1016/0031-9422(90)80115-W.