Linamarin synthase

linamarin synthase
Identifiers
EC number	2.4.1.63
CAS number	37277-68-2
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a linamarin synthase (EC 2.4.1.63) is an enzyme that catalyzes the chemical reaction

UDP-glucose + 2-hydroxy-2-methylpropanenitrile $\rightleftharpoons$ UDP + linamarin

Thus, the two substrates of this enzyme are UDP-glucose and 2-hydroxy-2-methylpropanenitrile, whereas its two products are UDP and linamarin.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:2-hydroxy-2-methylpropanenitrile beta-D-glucosyltransferase. Other names in common use include uridine diphosphoglucose-ketone glucosyltransferase, uridine diphosphate-glucose-ketone cyanohydrin, beta-glucosyltransferase, UDP glucose ketone cyanohydrin glucosyltransferase, UDP-glucose:ketone cyanohydrin beta-glucosyltransferase, and uridine diphosphoglucose-ketone cyanohydrin glucosyltransferase.

References

• Hahlbrock K, Conn EE (1970). "The biosynthesis of cyanogenic glycosides in higher plants. I Purification and properties of a uridine diphosphate-glucose-ketone cyanohydrin beta-glucosyltransferase from Linum usitatissimum L". J. Biol. Chem. 245 (5): 917–22. PMID 5417265.