Mannosylglycerate synthase

Mannosylglycerate synthase
Identifiers
EC number	2.4.1.269
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Mannosylglycerate synthase (EC 2.4.1.269) is an enzyme with systematic name GDP-mannose:D-glycerate 2-alpha-D-mannosyltransferase.^[1][2] This enzyme catalyses the following chemical reaction

GDP-mannose + D-glycerate $\rightleftharpoons$ GDP + 2-O-(alpha-D-mannopyranosyl)-D-glycerate

Depending on conditions mannosylglycerate synthase is more or less specific for the GDP-mannose and D-glycerate.

See also

• EC 2.4.1.217 (mannosyl-3-phosphoglycerate synthase)
• EC 3.1.3.70 (mannosyl-3-phosphoglycerate phosphatase)

References

1. Martins, L.O., Empadinhas, N., Marugg, J.D., Miguel, C., Ferreira, C., da Costa, M.S. and Santos, H. (1999). "Biosynthesis of mannosylglycerate in the thermophilic bacterium Rhodothermus marinus. Biochemical and genetic characterization of a mannosylglycerate synthase". J. Biol. Chem. 274 (50): 35407–35414. doi:10.1074/jbc.274.50.35407. PMID 10585410.
2. Flint, J., Taylor, E., Yang, M., Bolam, D.N., Tailford, L.E., Martinez-Fleites, C., Dodson, E.J., Davis, B.G., Gilbert, H.J. and Davies, G.J. (2005). "Structural dissection and high-throughput screening of mannosylglycerate synthase". Nat. Struct. Mol. Biol. 12 (7): 608–614. doi:10.1038/nsmb950. PMID 15951819.

External links

• Mannosylglycerate synthase at the US National Library of Medicine Medical Subject Headings (MeSH)