Sarsasapogenin 3β-glucosyltransferase
In enzymology, a sarsasapogenin 3β-glucosyltransferase (EC 2.4.1.193) is an enzyme that catalyzes the chemical reaction
- UDP-glucose + sarsasapogenin ⇌ UDP + sarsasapogenin 3-O-β-D-glucoside
Thus, the two substrates of this enzyme are UDP-glucose and sarsasapogenin [(3β,5β,25S)-spirostan-3-ol], whereas its two products are UDP and sarsasapogenin 3-O-β-D-glucoside.[1]
The enzyme was first isolated from the root of the common asparagus (Asparagus officinalis).[1] It is specific for substrate sterols with the uncommon 5β-configuration (sarsasapogenin and smilagenin), that is with a cis-linkage between the A and B rings of the steroid nucleus.[1]
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:(3β,5β,25S)-spirostan-3-ol 3-O-β-D-glucosyltransferase. This enzyme is also called uridine diphosphoglucose-sarsasapogenin glucosyltransferase.
References
- 1 2 3 Paczkowski, Cezary; Wojciechowski, Zdzisław A. (1988), "The occurrence of UDPG-dependent glucosyltransferase specific for sarsasapogenin in Asparagus officinalis", Phytochemistry 27 (9): 2743–47, doi:10.1016/0031-9422(88)80654-X .
|
|---|
| | Activity | |
|---|
| | Regulation | |
|---|
| | Classification | |
|---|
| | Types | |
|---|
|