- Wally Backman , 2B, 1993
- Cha Seung Baek , P, 2004, 2006–2008
- José Báez , 2B, 1977–1978
- Steve Balboni , 1B, 1988
- James Baldwin , P, 2002
- Wladimir Balentien , OF, 2007–2009
- Scott Bankhead , P, 1987–1991
- Floyd Bannister , P, 1979–1982
- Brandon Bantz , C, 2013
- Josh Bard , C, 2010
- Steve Baron , P, 2015–present
- Shawn Barton , P, 1992
- Shawn Barton , P, 1992
- Miguel Batista , P, 2007–2009
- Jason Bay , OF, 2013
- Charlie Beamon, Jr. , DH, 1978–1979
- Dave Beard , P, 1984
- Jim Beattie , P, 1980–1986
- Blake Beavan , P, 2011–2014
- Érik Bédard , P, 2008–2011
- Joe Beimel , P, 2014–present
- Tim Belcher , P, 1995
- David Bell , 3B/2B, 1998–2001
- Adrián Beltré , 3B, 2005–2009
- Andy Benes , P, 1995
- Juan Beníquez , OF, 1980
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- Armando Benítez , P, 2003
- Tony Bernazard , 2B, 1983
- Juan Bernhardt , DH, 1977–1979
- Karl Best , P, 1983–1986
- Yuniesky Betancourt , SS, 2005–2009
- Bud Black , P, 1981
- Travis Blackley , P, 2004
- Henry Blanco , C, 2013
- Willie Bloomquist , IF/OF, 2002–2008, 2014–2015
- Mike Blowers , 3B, 1992–1995, 1997, 1999
- Hiram Bocachica , OF, 2004
- Bruce Bochte , 1B/OF, 1978–1982
- T. J. Bohn , OF, 2006
- Jeremy Bonderman , P, 2013
- Barry Bonnell , OF, 1984–1986
- Bret Boone , 2B, 1992–1993, 2001–2005
- Joe Borchard , OF, 2006
- Pat Borders , C, 2001–2004, 2005
- Rich Bordi , P, 1982
- Chris Bosio , P, 1993–1996
- Shawn Boskie , P, 1994
- Thad Bosley , OF, 1982
- Rafael Bournigal , SS, 1999
- Milton Bradley , OF, 2010–2011
- Phil Bradley , OF, 1983–1987
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- Scott Bradley , C, 1986–1992
- Darren Bragg , OF, 1994–1996
- Roy Branch , P, 1979
- Mickey Brantley , OF, 1986–1989
- Russell Branyan , 1B, 2009–2010
- Steve Braun , OF, 1977–1978
- Greg Briley , OF, 1988–1992
- Ben Broussard , 1B, 2006–2007
- Bobby Brown , OF, 1982
- Kevin D. Brown , P, 1992
- Mike Brown , P, 1986–1987
- Tom Brown , P, 1978
- Mike Brumley , SS, 1990
- Jaime Bubela , OF, 2005
- John Buck , C, 2014
- Jay Buhner , OF, 1988–2001
- Bud Bulling , C, 1981–1983
- Jim Bullinger , P, 1998
- Melvin Bunch , P, 1999
- Dave Burba , P, 1990–1991
- Jamie Burke , C, 2007–2008, 2009
- Steve Burke , P, 1977–1978
- Jeff Burroughs , OF, 1981
- Eric Byrnes , OF, 2010
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